Hemodynamic response to β-blockers in severe sepsis and septic shock: A review of current literature.
Heart failure
Hemodynamics
Microcirculation, V-A coupling
Septic shock
β-blocker
Journal
Journal of critical care
ISSN: 1557-8615
Titre abrégé: J Crit Care
Pays: United States
ID NLM: 8610642
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
10
09
2018
revised:
03
12
2018
accepted:
04
12
2018
pubmed:
13
12
2018
medline:
23
4
2020
entrez:
13
12
2018
Statut:
ppublish
Résumé
The administration of β-blockers in patients with sepsis is a trending topic in intensive care medicine since the landmark study by Morelli and colleagues, showing a striking decrease in 28-day mortality compared to standard care. While the available evidence suggests that the use of β-blockers in septic shock is safe, the effects on hemodynamics are controversial. In this paper, we review the effect of β-blockade in septic shock on hemodynamics from animal models to critically ill patients.
Identifiants
pubmed: 30540967
pii: S0883-9441(18)31056-6
doi: 10.1016/j.jcrc.2018.12.003
pii:
doi:
Substances chimiques
Adrenergic beta-Antagonists
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
138-143Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.