Cytomegalovirus Exposure in the Elderly Does Not Reduce CD8 T Cell Repertoire Diversity.


Journal

Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R

Informations de publication

Date de publication:
15 01 2019
Historique:
received: 15 02 2018
accepted: 04 11 2018
pubmed: 14 12 2018
medline: 29 10 2019
entrez: 14 12 2018
Statut: ppublish

Résumé

With age, the immune system becomes less effective, causing increased susceptibility to infection. Chronic CMV infection further impairs immune function and is associated with increased mortality in the elderly. CMV exposure elicits massive CD8

Identifiants

pubmed: 30541882
pii: jimmunol.1800217
doi: 10.4049/jimmunol.1800217
pmc: PMC6321841
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

476-483

Subventions

Organisme : NIGMS NIH HHS
ID : T32 GM007266
Pays : United States

Informations de copyright

Copyright © 2019 The Authors.

Références

J Immunol. 2007 Apr 1;178(7):4455-65
pubmed: 17372003
J Exp Med. 2004 Nov 15;200(10):1347-58
pubmed: 15545358
Immunity. 2008 Oct 17;29(4):650-9
pubmed: 18957267
PLoS One. 2011 Feb 17;6(2):e16103
pubmed: 21379581
Immunity. 2008 Dec 19;29(6):848-62
pubmed: 19100699
Nat Immunol. 2013 May;14(5):428-36
pubmed: 23598398
J Exp Med. 2008 Mar 17;205(3):711-23
pubmed: 18332179
Exp Gerontol. 2004 Apr;39(4):607-13
pubmed: 15050296
PLoS Pathog. 2012;8(8):e1002849
pubmed: 22916012
Clin Immunol. 2008 Apr;127(1):107-18
pubmed: 18222733
J Immunol. 2012 Dec 1;189(11):5356-66
pubmed: 23087407
Clin Microbiol Rev. 2009 Jan;22(1):76-98, Table of Contents
pubmed: 19136435
J Immunol. 2002 Aug 15;169(4):1984-92
pubmed: 12165524
Nat Commun. 2013;4:2680
pubmed: 24157944
Blood. 2015 Jun 18;125(25):3835-50
pubmed: 25852054
Nat Biotechnol. 2013 Jul;31(7):623-9
pubmed: 23748502
Nat Rev Immunol. 2008 Jul;8(7):512-22
pubmed: 18469829
J Immunol. 2016 May 1;196(9):3920-6
pubmed: 27001957
Semin Immunol. 2012 Oct;24(5):356-64
pubmed: 22554418
Nature. 1992 Nov 19;360(6401):264-5
pubmed: 1436108
Curr Opin Immunol. 2005 Oct;17(5):480-5
pubmed: 16098721
Sci Rep. 2016 Aug 02;6:30842
pubmed: 27480406
J Immunol. 2013 Jun 1;190(11):5363-72
pubmed: 23636061
Blood. 2004 Aug 15;104(4):1075-82
pubmed: 15039282
J Gerontol A Biol Sci Med Sci. 2005 May;60(5):556-65
pubmed: 15972602
J Exp Med. 2005 Sep 5;202(5):673-85
pubmed: 16147978
J Virol. 2012 Jan;86(2):1001-9
pubmed: 22072753
Clin Infect Dis. 2010 Jun 1;50(11):1439-47
pubmed: 20426575
J Immunol. 2005 Jun 1;174(11):7446-52
pubmed: 15905594
Hum Vaccin Immunother. 2016 Mar 3;12(3):682-90
pubmed: 26588038
Blood. 2000 May 1;95(9):2860-8
pubmed: 10779432
Eur J Immunol. 2013 Nov;43(11):2797-809
pubmed: 24258910
J Immunol. 2006 Feb 15;176(4):2645-53
pubmed: 16456027
Nat Genet. 2017 May;49(5):659-665
pubmed: 28369038
J Virol. 2015 Apr;89(8):4517-26
pubmed: 25653453
Sci Transl Med. 2012 May 16;4(134):134ra63
pubmed: 22593176
Front Immunol. 2017 Jun 26;8:733
pubmed: 28694811
J Immunol. 2010 Jun 15;184(12):6739-45
pubmed: 20483749
Aging Dis. 2012 Feb;3(1):68-90
pubmed: 22500272
J Immunol. 2004 Dec 15;173(12):7481-9
pubmed: 15585874
J Gen Virol. 2011 Dec;92(Pt 12):2746-2756
pubmed: 21813708
Semin Hematol. 2017 Jan;54(1):33-38
pubmed: 28088985
Blood. 2007 Jul 1;110(1):201-10
pubmed: 17371945
PLoS Pathog. 2012 Sep;8(9):e1002889
pubmed: 23028307
Aging Cell. 2013 Jun;12(3):381-7
pubmed: 23442093
Immunology. 2011 Jan;132(1):27-38
pubmed: 20738423
J Immunol. 1999 Jun 15;162(12):7080-7
pubmed: 10358151
Am J Epidemiol. 2010 May 15;171(10):1144-52
pubmed: 20400465
J Virol. 2005 Mar;79(6):3675-83
pubmed: 15731261
PLoS One. 2011;6(10):e26558
pubmed: 22028907
Blood. 2003 Nov 1;102(9):3244-51
pubmed: 12869504
Sci Transl Med. 2010 Sep 1;2(47):47ra64
pubmed: 20811043
Curr Opin Immunol. 2010 Aug;22(4):507-13
pubmed: 20667703
J Immunol Methods. 2012 Jan 31;375(1-2):14-9
pubmed: 21945395

Auteurs

Paul Lindau (P)

Molecular and Cellular Biology Graduate Program, University of Washington School of Medicine, Seattle, WA 98195; plindau@uw.edu hrobins@fredhutch.org.
Herbold Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.

Rithun Mukherjee (R)

Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA 98101.

Miriam V Gutschow (MV)

Herbold Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.

Marissa Vignali (M)

Adaptive Biotechnologies, Seattle, WA 98102.

Edus H Warren (EH)

Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
Department of Medicine, University of Washington, Seattle, WA 98195; and.

Stanley R Riddell (SR)

Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
Department of Medicine, University of Washington, Seattle, WA 98195; and.

Karen W Makar (KW)

Bill and Melinda Gates Foundation, Seattle, WA 98109.

Cameron J Turtle (CJ)

Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
Department of Medicine, University of Washington, Seattle, WA 98195; and.

Harlan S Robins (HS)

Herbold Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109; plindau@uw.edu hrobins@fredhutch.org.
Adaptive Biotechnologies, Seattle, WA 98102.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH