Predicting one-year mortality in heart failure using the 'Surprise Question': a prospective pilot study.


Journal

European journal of heart failure
ISSN: 1879-0844
Titre abrégé: Eur J Heart Fail
Pays: England
ID NLM: 100887595

Informations de publication

Date de publication:
02 2019
Historique:
received: 30 05 2018
revised: 19 08 2018
accepted: 05 10 2018
pubmed: 15 12 2018
medline: 22 5 2019
entrez: 15 12 2018
Statut: ppublish

Résumé

The Surprise Question: 'would you be surprised if this patient were to die within the next year?' has been shown to predict mortality in patients with chronic kidney disease and cancer. This prospective study aimed to determine whether the Surprise Question could identify heart failure patients with a prognosis of less than 1 year, and whether the Surprise Question can be used by different healthcare professionals. Overall, 129 consecutive patients admitted with decompensated heart failure were included. Doctors and nurses were asked to provide a 'surprised' or 'not surprised' response to the Surprise Question for each patient. Patients were followed up until death or 1 year following study inclusion. The sensitivity, specificity, positive predictive value and negative predictive value of the Surprise Question were assessed. Cox regression was used to determine covariates significantly associated with survival. The Surprise Question showed excellent sensitivity (0.85) and negative predictive value (0.88) but only fair specificity (0.59) and positive predictive value (0.52) when asked of cardiologists. There were similar levels of accuracy between doctors and specialist nurses. The Surprise Question was significantly associated with all-cause mortality in multivariate regression analysis (hazard ratio 2.8, 95% confidence interval 1.0-7.9, P = 0.046). This study demonstrates that the Surprise Question can identify heart failure patients within the last year of life. Despite over-classification of patients into the 'not surprised' category, the Surprise Question identified nearly all patients who were within the last year of life, whilst also accurately identifying those unlikely to die.

Sections du résumé

BACKGROUND
The Surprise Question: 'would you be surprised if this patient were to die within the next year?' has been shown to predict mortality in patients with chronic kidney disease and cancer. This prospective study aimed to determine whether the Surprise Question could identify heart failure patients with a prognosis of less than 1 year, and whether the Surprise Question can be used by different healthcare professionals.
METHODS AND RESULTS
Overall, 129 consecutive patients admitted with decompensated heart failure were included. Doctors and nurses were asked to provide a 'surprised' or 'not surprised' response to the Surprise Question for each patient. Patients were followed up until death or 1 year following study inclusion. The sensitivity, specificity, positive predictive value and negative predictive value of the Surprise Question were assessed. Cox regression was used to determine covariates significantly associated with survival. The Surprise Question showed excellent sensitivity (0.85) and negative predictive value (0.88) but only fair specificity (0.59) and positive predictive value (0.52) when asked of cardiologists. There were similar levels of accuracy between doctors and specialist nurses. The Surprise Question was significantly associated with all-cause mortality in multivariate regression analysis (hazard ratio 2.8, 95% confidence interval 1.0-7.9, P = 0.046).
CONCLUSION
This study demonstrates that the Surprise Question can identify heart failure patients within the last year of life. Despite over-classification of patients into the 'not surprised' category, the Surprise Question identified nearly all patients who were within the last year of life, whilst also accurately identifying those unlikely to die.

Identifiants

pubmed: 30548129
doi: 10.1002/ejhf.1353
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

227-234

Subventions

Organisme : British Heart Foundation
ID : FS/12/80/29821
Pays : United Kingdom
Organisme : British Heart Foundation
ID : FS/18/44/33792
Pays : United Kingdom
Organisme : Department of Health
ID : HCS DRF-2014-05-006
Pays : United Kingdom
Organisme : Department of Health
ID : NIHR-CS-012-032
Pays : United Kingdom

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn

Informations de copyright

© 2018 The Authors. European Journal of Heart Failure © 2018 European Society of Cardiology.

Auteurs

Sam Straw (S)

Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

Rowenna Byrom (R)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

John Gierula (J)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Maria F Paton (MF)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Aaron Koshy (A)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Richard Cubbon (R)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Michael Drozd (M)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Mark Kearney (M)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Klaus K Witte (KK)

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

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