Molecular Imaging of mGluR5 Availability with [


Journal

Cellular and molecular neurobiology
ISSN: 1573-6830
Titre abrégé: Cell Mol Neurobiol
Pays: United States
ID NLM: 8200709

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 23 08 2018
accepted: 10 12 2018
pubmed: 16 12 2018
medline: 30 4 2019
entrez: 16 12 2018
Statut: ppublish

Résumé

Many PET tracers enable determination of fluctuations in neurotransmitter release, yet glutamate specifically can not be visualized in a noninvasive manner. Several studies point to the possibility of visualizing fluctuations in glutamate release by changes in affinity of the mGluR5 radioligand [

Identifiants

pubmed: 30552621
doi: 10.1007/s10571-018-0645-y
pii: 10.1007/s10571-018-0645-y
doi:

Substances chimiques

3-(6-methylpyridin-2-ylethynyl)cyclohex-2-enone-O-methyloxime 0
Carbon Radioisotopes 0
Carbon-11 0
Oximes 0
Pyridines 0
Receptor, Metabotropic Glutamate 5 0
Glutamine 0RH81L854J
Glutaminase EC 3.5.1.2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

255-263

Subventions

Organisme : Fonds Wetenschappelijk Onderzoek
ID : V4.228.16N

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Auteurs

Lauren Kosten (L)

Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.

Steven Deleye (S)

Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.

Sigrid Stroobants (S)

Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
Department of Nuclear Medicine, University Hospital Antwerp, Antwerp, Belgium.

Leonie Wyffels (L)

Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
Department of Nuclear Medicine, University Hospital Antwerp, Antwerp, Belgium.

Susana Mingote (S)

Department of Psychiatry, Columbia University, New York, USA.
Molecular Therapeutics, NYS Psychiatric Institute, New York, USA.

Stephen Rayport (S)

Department of Psychiatry, Columbia University, New York, USA.
Molecular Therapeutics, NYS Psychiatric Institute, New York, USA.

Steven Staelens (S)

Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium. steven.staelens@uantwerpen.be.

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Classifications MeSH