Thiol functionalization of flaxseed mucilage: Preparation, characterization and evaluation as mucoadhesive polymer.

Adhesiveness Calorimetry, Differential Scanning Diclofenac / pharmacology Drug Liberation Flax / chemistry Magnetic Resonance Spectroscopy Mucus / chemistry Plant Mucilage / chemistry Polymers / chemistry Spectroscopy, Fourier Transform Infrared Sulfhydryl Compounds / chemistry X-Ray Diffraction
Flaxseed Mucoadhesion Thiolation

Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
01 Apr 2019
Historique:
received: 16 08 2018
revised: 11 12 2018
accepted: 13 12 2018
pubmed: 18 12 2018
medline: 1 6 2019
entrez: 18 12 2018
Statut: ppublish

Résumé

The aim of present study is to browse mucoadhesive potential of flaxseed mucilage after thiol functionalization. Thiol-derivatization of flaxseed mucilage (FSM) polysaccharide was obtained by esterification with thioglycolic acid. Thiolation of FSM was confirmed by -SH stretch in FTIR spectra at 2549.01 cm

Identifiants

DOI: 10.1016/j.ijbiomac.2018.12.116 PMID: 30557645
pubmed: 30557645
pii: S0141-8130(18)34308-3
doi: 10.1016/j.ijbiomac.2018.12.116
pii:
doi:

Substances chimiques

Plant Mucilage 0
Polymers 0
Sulfhydryl Compounds 0
Diclofenac 144O8QL0L1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

101-106

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Rupa Devi (R)

Drug Delivery Research Laboratory, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, India.

Meenakshi Bhatia (M)

Drug Delivery Research Laboratory, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, India. Electronic address: meenaxibhatia@gjust.org.

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Propriétés de surface › Adhésivité › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse thermique différentielle › Calorimétrie différentielle à balayage › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides carbocycliques › Phénylacétates › Diclofenac › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Libération de médicament › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Rosanae › Malpighiales › Linaceae › Lin › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Liquides et sécrétions biologiques › Sécrétions corporelles › Mucus › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Mucilage des plantes › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectrophotométrie › Spectrophotométrie IR › Spectroscopie infrarouge à transformée de Fourier › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Thiols › Thiol functionalization of flaxseed mucilage:...
questionsmedicales.fr › Phénomènes chimiques › Diffraction des rayons X › Thiol functionalization of flaxseed mucilage:...