The maternal inheritance of Alto Paraná revealed by full mitogenome sequences.
EMPOP
Forensic science
Haplogroups
Mitochondrial DNA
Mitogenomes
Journal
Forensic science international. Genetics
ISSN: 1878-0326
Titre abrégé: Forensic Sci Int Genet
Pays: Netherlands
ID NLM: 101317016
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
16
10
2018
revised:
08
12
2018
accepted:
18
12
2018
pubmed:
30
12
2018
medline:
15
3
2019
entrez:
30
12
2018
Statut:
ppublish
Résumé
Most studies on maternal lineages of South America populations are restricted to control region (CR) markers and, for some geographical regions, the number of studied samples does not adequately represent the existing diversity. This is the case of mitochondrial DNA (mtDNA) studies on Paraguay that are limited to two Native ethnic groups. To overcome this deficiency, we analysed the mitogenomes from 105 individuals living in Alto Paraná, the second most populated department of the country. Using the Precision ID mtDNA Whole Genome Panel, the molecule was sequenced on Ion S5. The majority of the haplotypes belong to the Native American lineages A, B, C and D. Analyses of maximum parsimony using mitogenome data retrieved from publications and in The 1000 Genomes Project showed a high number of new native American subclades in Paraguay. Also, none of the haplotypes found in Alto Paraná match the remaining South American samples, which include admixed populations from Colombia, Peru and Ecuador, and natives from Colombia and Ecuador. F
Identifiants
pubmed: 30594063
pii: S1872-4973(18)30548-9
doi: 10.1016/j.fsigen.2018.12.007
pii:
doi:
Substances chimiques
DNA, Mitochondrial
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
66-72Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.