Long-term results of surgical treatment of secondary severe mitral regurgitation in patients with end-stage heart failure: Advantage of prosthesis insertion.


Journal

Archives of cardiovascular diseases
ISSN: 1875-2128
Titre abrégé: Arch Cardiovasc Dis
Pays: Netherlands
ID NLM: 101465655

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 16 03 2018
revised: 15 06 2018
accepted: 05 09 2018
pubmed: 3 1 2019
medline: 23 4 2019
entrez: 3 1 2019
Statut: ppublish

Résumé

Surgical treatment of secondary mitral regurgitation (SMR) is controversial. To analyse outcome after undersizing annuloplasty (UA) and mitral valve replacement (MVR). Consecutive patients operated on for severe SMR, with left ventricular ejection fraction (LVEF)<40% and refractory CHF, were included. Endpoints were in-hospital mortality, mid-term cardiovascular (CV) mortality, evolution of LV variables and recurrence of mitral regurgitation (MR). 59 patients were included (mean age 65±10 years, preoperative LVEF 36±6%; effective regurgitant orifice [ERO] 41±17 mm Surgical treatment of SMR can be performed with acceptable operative risk and mid-term survival in severe heart failure, even if there is no indication for revascularization. MVR is associated with significant reverse remodelling, and UA with prohibitive risk of MR recurrence.

Sections du résumé

BACKGROUND BACKGROUND
Surgical treatment of secondary mitral regurgitation (SMR) is controversial.
AIM OBJECTIVE
To analyse outcome after undersizing annuloplasty (UA) and mitral valve replacement (MVR).
METHODS METHODS
Consecutive patients operated on for severe SMR, with left ventricular ejection fraction (LVEF)<40% and refractory CHF, were included. Endpoints were in-hospital mortality, mid-term cardiovascular (CV) mortality, evolution of LV variables and recurrence of mitral regurgitation (MR).
RESULTS RESULTS
59 patients were included (mean age 65±10 years, preoperative LVEF 36±6%; effective regurgitant orifice [ERO] 41±17 mm
CONCLUSIONS CONCLUSIONS
Surgical treatment of SMR can be performed with acceptable operative risk and mid-term survival in severe heart failure, even if there is no indication for revascularization. MVR is associated with significant reverse remodelling, and UA with prohibitive risk of MR recurrence.

Identifiants

pubmed: 30600216
pii: S1875-2136(18)30190-6
doi: 10.1016/j.acvd.2018.09.006
pii:
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

95-103

Informations de copyright

Copyright © 2018. Published by Elsevier Masson SAS.

Auteurs

Alexis Théron (A)

Department of Cardiac Surgery, La Timone Hospital, AP-HM, 13005 Marseille, France.

Pierre Morera (P)

Department of Cardiac Surgery, La Timone Hospital, AP-HM, 13005 Marseille, France.

Noémie Resseguier (N)

Department of Cardiac Surgery, La Timone Hospital, AP-HM, 13005 Marseille, France.

Dominique Grisoli (D)

Department of Cardiac Surgery, La Timone Hospital, AP-HM, 13005 Marseille, France.

Giulia Norscini (G)

Department of Cardiology, La Timone Hospital, AP-HM, 13005 Marseille, France.

Alberto Riberi (A)

Department of Cardiac Surgery, La Timone Hospital, AP-HM, 13005 Marseille, France.

Frédéric Collart (F)

Department of Cardiac Surgery, La Timone Hospital, AP-HM, 13005 Marseille, France.

Gilbert Habib (G)

Department of Cardiology, La Timone Hospital, AP-HM, 13005 Marseille, France.

Jean-François Avierinos (JF)

Department of Cardiology, La Timone Hospital, AP-HM, 13005 Marseille, France. Electronic address: jfavierinos@ap-hm.fr.

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