Effect of Compound Probiotics and Mycotoxin Degradation Enzymes on Alleviating Cytotoxicity of Swine Jejunal Epithelial Cells Induced by Aflatoxin B₁ and Zearalenone.
Aflatoxin B1
/ toxicity
Animals
Apoptosis Regulatory Proteins
/ genetics
Aspergillus oryzae
/ enzymology
Cell Line
Cell Survival
/ drug effects
Epithelial Cells
/ drug effects
Interleukin-6
/ genetics
Jejunum
/ cytology
Membrane Transport Proteins
/ genetics
Occludin
/ genetics
Probiotics
/ pharmacology
Swine
Zearalenone
/ toxicity
Zonula Occludens-1 Protein
/ genetics
IPEC-J2 cells
Mycotoxins
biodegradation
mycotoxin degradation enzymes
probiotics
Journal
Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765
Informations de publication
Date de publication:
01 01 2019
01 01 2019
Historique:
received:
01
10
2018
revised:
19
12
2018
accepted:
24
12
2018
entrez:
6
1
2019
pubmed:
6
1
2019
medline:
18
12
2019
Statut:
epublish
Résumé
Zearalenone (ZEA) and aflatoxin B₁ (AFB₁) are two main kinds of mycotoxins widely existing in grain and animal feed that cause a lot of economic loss and health problems for animals and humans. In order to alleviate the cytotoxic effects of AFB₁ and ZEA on swine jejunal epithelial cells (IPEC-J2), the combination of a cell-free supernatant of compound probiotics (CFSCP) with mycotoxin degradation enzymes (MDEs) from
Identifiants
pubmed: 30609651
pii: toxins11010012
doi: 10.3390/toxins11010012
pmc: PMC6356961
pii:
doi:
Substances chimiques
Apoptosis Regulatory Proteins
0
Interleukin-6
0
Membrane Transport Proteins
0
Occludin
0
Zonula Occludens-1 Protein
0
Zearalenone
5W827M159J
Aflatoxin B1
9N2N2Y55MH
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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