Combination of assist use of short-acting beta-2 agonists inhalation and guidance based on patient-specific restrictions in daily behavior: Impact on physical activity of Japanese patients with chronic obstructive pulmonary disease.
Bronchodilator
Coaching
Daily behavior
Dynamic hyperinflation
Shortness of breath
Journal
Respiratory investigation
ISSN: 2212-5353
Titre abrégé: Respir Investig
Pays: Netherlands
ID NLM: 101581124
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
12
06
2018
revised:
26
11
2018
accepted:
07
12
2018
pubmed:
8
1
2019
medline:
8
6
2019
entrez:
8
1
2019
Statut:
ppublish
Résumé
Assist use of inhaled short-acting beta 2 agonists (SABAs) is reportedly effective for preventing shortness of breath on exertion in chronic obstructive pulmonary disease (COPD) patients. However, it is unclear what strategy would be useful for improving physical activity in such patients. The aim is to investigate the effects of assisted use of SABA (procaterol) on physical activity in Japanese COPD patients targeting patient-specific restrictions in daily behavior. Fourteen patients with stable COPD (age: 72.1±1.5, %FEV The strategy significantly improved the physical activity level, assessed using the values of the metabolic equivalents (METs) multiplied by physical activity endurance, at ≥3.0 METs (p<0.05), and physical activity endurance at ≥2.5 and ≥3.0 METs, (p<0.05, p<0.05, respectively). The degree of improvement of physical activity level was significantly positively correlated with the baseline %FVC and %FEV Assist use of SABA targeting patient-specific restrictions, particularly when better lung function is still preserved, could be a useful approach for improving physical activity in patients with COPD.
Sections du résumé
BACKGROUND
BACKGROUND
Assist use of inhaled short-acting beta 2 agonists (SABAs) is reportedly effective for preventing shortness of breath on exertion in chronic obstructive pulmonary disease (COPD) patients. However, it is unclear what strategy would be useful for improving physical activity in such patients. The aim is to investigate the effects of assisted use of SABA (procaterol) on physical activity in Japanese COPD patients targeting patient-specific restrictions in daily behavior.
METHODS
METHODS
Fourteen patients with stable COPD (age: 72.1±1.5, %FEV
RESULTS
RESULTS
The strategy significantly improved the physical activity level, assessed using the values of the metabolic equivalents (METs) multiplied by physical activity endurance, at ≥3.0 METs (p<0.05), and physical activity endurance at ≥2.5 and ≥3.0 METs, (p<0.05, p<0.05, respectively). The degree of improvement of physical activity level was significantly positively correlated with the baseline %FVC and %FEV
CONCLUSIONS
CONCLUSIONS
Assist use of SABA targeting patient-specific restrictions, particularly when better lung function is still preserved, could be a useful approach for improving physical activity in patients with COPD.
Identifiants
pubmed: 30612948
pii: S2212-5345(18)30108-4
doi: 10.1016/j.resinv.2018.12.001
pii:
doi:
Substances chimiques
Adrenergic beta-2 Receptor Agonists
0
Procaterol
X7I3EMM5K0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
133-139Informations de copyright
Copyright © 2018 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.