Strong Inhibition of Cholera Toxin B Subunit by Affordable, Polymer-Based Multivalent Inhibitors.


Journal

Bioconjugate chemistry
ISSN: 1520-4812
Titre abrégé: Bioconjug Chem
Pays: United States
ID NLM: 9010319

Informations de publication

Date de publication:
20 03 2019
Historique:
pubmed: 11 1 2019
medline: 1 1 2020
entrez: 11 1 2019
Statut: ppublish

Résumé

Cholera is a potentially fatal bacterial infection that affects a large number of people in developing countries. It is caused by the cholera toxin (CT), an AB

Identifiants

pubmed: 30629410
doi: 10.1021/acs.bioconjchem.8b00902
pmc: PMC6429436
doi:

Substances chimiques

Galactosides 0
Ligands 0
Polymers 0
Cholera Toxin 9012-63-9

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

785-792

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Auteurs

Diksha Haksar (D)

Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences , Utrecht University , Universiteitsweg 99 , 3584 CG Utrecht , The Netherlands.

Eyleen de Poel (E)

Department of Pediatric Pulmonology, Regenerative Medicine Center Utrecht , University Medical Centre Utrecht , Lundlaan 6 , 3508 GA Utrecht , The Netherlands.

Linda Quarles van Ufford (LQ)

Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences , Utrecht University , Universiteitsweg 99 , 3584 CG Utrecht , The Netherlands.

Sumati Bhatia (S)

Institut für Chemie und Biochemie Organische Chemie , Freie Universität at Berlin , Takustr. 3 , 14195 Berlin , Germany.

Rainer Haag (R)

Institut für Chemie und Biochemie Organische Chemie , Freie Universität at Berlin , Takustr. 3 , 14195 Berlin , Germany.

Jeffrey Beekman (J)

Department of Pediatric Pulmonology, Regenerative Medicine Center Utrecht , University Medical Centre Utrecht , Lundlaan 6 , 3508 GA Utrecht , The Netherlands.

Roland J Pieters (RJ)

Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences , Utrecht University , Universiteitsweg 99 , 3584 CG Utrecht , The Netherlands.

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Classifications MeSH