Effects of pH of processing-medium on re-dispersion of spray dried, crystalline nanoparticles of pure naproxen.

Anti-Inflammatory Agents, Non-Steroidal / chemistry Crystallization Desiccation Drug Compounding Hydrogen-Ion Concentration Nanoparticles / chemistry Naproxen / chemistry
Nanoparticles Particle size Poorly-soluble drug Re-dispersion Spray drying pH

Journal

International journal of pharmaceutics
ISSN: 1873-3476
Titre abrégé: Int J Pharm
Pays: Netherlands
ID NLM: 7804127

Informations de publication

Date de publication:
10 Mar 2019
Historique:
received: 06 11 2018
revised: 21 12 2018
accepted: 28 12 2018
pubmed: 15 1 2019
medline: 14 6 2019
entrez: 15 1 2019
Statut: ppublish

Résumé

Crystalline nanodispersions of naproxen stabilized with hydroxypropyl cellulose were prepared at different pHs both below and above the pK

Identifiants

DOI: 10.1016/j.ijpharm.2018.12.084 PMID: 30641175
pubmed: 30641175
pii: S0378-5173(19)30022-5
doi: 10.1016/j.ijpharm.2018.12.084
pii:
doi:

Substances chimiques

Anti-Inflammatory Agents, Non-Steroidal 0
Naproxen 57Y76R9ATQ

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

261-267

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Veronika Braig (V)

Division of Pharmaceutics, Friedrich-Alexander-University, Erlangen, Germany.

Christoph Konnerth (C)

Institute of Particle Technology, Friedrich-Alexander-University, Erlangen, Germany.

Wolfgang Peukert (W)

Institute of Particle Technology, Friedrich-Alexander-University, Erlangen, Germany.

Geoffrey Lee (G)

Division of Pharmaceutics, Friedrich-Alexander-University, Erlangen, Germany. Electronic address: geoff.lee@fau.de.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antirhumatismaux › Anti-inflammatoires non stéroïdiens › Effects of pH of processing-medium on...
questionsmedicales.fr › Phénomènes chimiques › Cristallisation › Effects of pH of processing-medium on...
questionsmedicales.fr › Phénomènes chimiques › Dessiccation › Effects of pH of processing-medium on...
questionsmedicales.fr › Techniques d'investigation › Préparation de médicament › Effects of pH of processing-medium on...
questionsmedicales.fr › Phénomènes chimiques › Concentration en ions d'hydrogène › Effects of pH of processing-medium on...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Effects of pH of processing-medium on...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Naphtalènes › Acides naphtalèneacétiques › Naproxène › Effects of pH of processing-medium on...