Long-term survival rates of patients undergoing vitrectomy for diabetic retinopathy in an Australian population: a population-based audit.
Adult
Aged
Aged, 80 and over
Cause of Death
Diabetic Retinopathy
/ mortality
Ethnicity
Female
Follow-Up Studies
Humans
Male
Medical Audit
/ statistics & numerical data
Middle Aged
Native Hawaiian or Other Pacific Islander
Northern Territory
/ epidemiology
Private Practice
Retrospective Studies
Risk Factors
South Australia
/ epidemiology
Survival Rate
Tertiary Care Centers
Vitrectomy
/ mortality
Young Adult
Australia
diabetic retinopathy
long-term mortality
vitrectomy
Journal
Clinical & experimental ophthalmology
ISSN: 1442-9071
Titre abrégé: Clin Exp Ophthalmol
Pays: Australia
ID NLM: 100896531
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
29
10
2018
revised:
08
01
2019
accepted:
09
01
2019
pubmed:
22
1
2019
medline:
1
8
2020
entrez:
22
1
2019
Statut:
ppublish
Résumé
Five-year survival rates in patients undergoing vitrectomy for diabetic retinopathy (DR) vary from 68% to 95%. No study has been conducted in an Australian population. We aimed to determine the survival rates of patients undergoing diabetic vitrectomy in an Australian population. Retrospective audit, tertiary centre hospitals and private practices. All individuals in South Australia and the Northern Territory who underwent their first vitrectomy for diabetic complications between January 1, 2007 and December 31, 2011. An audit of all eligible participants has been completed previously. Survival status as of July 6, 2018 and cause of death were obtained using SA/NT DataLink. Kaplan-Meier survival curves and multivariate cox-regressions were used to analyse survival rates and identify risk factors for mortality. Five-, seven- and nine-year survival rates. The 5-, 7- and 9-year survival rates were 84.4%, 77.9% and 74.7%, respectively. The most common cause of death was cardiovascular disease. Associated with increased mortality independent of age were Indigenous ethnicity (HR = 2.04, 95% confidence interval [CI]: 1.17-3.57, P = 0.012), chronic renal failure (HR = 1.76, 95% CI: 1.07-2.89, P = 0.026) and renal failure requiring dialysis (HR = 2.32, 95% CI: 1.25-4.32, P = 0.008). Long-term survival rates after diabetic vitrectomy in Australia are similar to rates reported in other populations. Indigenous ethnicity and chronic renal failure were the most significant factors associated with long-term mortality. This information can guide allocation of future resources to improve the prognosis of these high risk groups.
Sections du résumé
IMPORTANCE
Five-year survival rates in patients undergoing vitrectomy for diabetic retinopathy (DR) vary from 68% to 95%. No study has been conducted in an Australian population.
BACKGROUND
We aimed to determine the survival rates of patients undergoing diabetic vitrectomy in an Australian population.
DESIGN
Retrospective audit, tertiary centre hospitals and private practices.
PARTICIPANTS
All individuals in South Australia and the Northern Territory who underwent their first vitrectomy for diabetic complications between January 1, 2007 and December 31, 2011.
METHODS
An audit of all eligible participants has been completed previously. Survival status as of July 6, 2018 and cause of death were obtained using SA/NT DataLink. Kaplan-Meier survival curves and multivariate cox-regressions were used to analyse survival rates and identify risk factors for mortality.
MAIN OUTCOME MEASURES
Five-, seven- and nine-year survival rates.
RESULTS
The 5-, 7- and 9-year survival rates were 84.4%, 77.9% and 74.7%, respectively. The most common cause of death was cardiovascular disease. Associated with increased mortality independent of age were Indigenous ethnicity (HR = 2.04, 95% confidence interval [CI]: 1.17-3.57, P = 0.012), chronic renal failure (HR = 1.76, 95% CI: 1.07-2.89, P = 0.026) and renal failure requiring dialysis (HR = 2.32, 95% CI: 1.25-4.32, P = 0.008).
CONCLUSIONS AND RELEVANCE
Long-term survival rates after diabetic vitrectomy in Australia are similar to rates reported in other populations. Indigenous ethnicity and chronic renal failure were the most significant factors associated with long-term mortality. This information can guide allocation of future resources to improve the prognosis of these high risk groups.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
598-604Commentaires et corrections
Type : CommentIn
Type : CommentIn
Type : ErratumIn
Informations de copyright
© 2019 Royal Australian and New Zealand College of Ophthalmologists.