Pharmacotherapy for Hoarding Disorder: How did the Picture Change since its Excision from OCD?
Hoarding disorder
atomoxetine
cognitive-behavioural therapy
drug treatment
methylphenidate
obsessive-compulsive disorder
venlafaxine.
Journal
Current neuropharmacology
ISSN: 1875-6190
Titre abrégé: Curr Neuropharmacol
Pays: United Arab Emirates
ID NLM: 101157239
Informations de publication
Date de publication:
2019
2019
Historique:
received:
26
10
2018
revised:
21
12
2018
accepted:
17
01
2019
pubmed:
27
1
2019
medline:
16
1
2020
entrez:
26
1
2019
Statut:
ppublish
Résumé
This brief review deals with the various issues that contributed to the creation of the new Diagnostic and Statistical Manual condition of hoarding disorder (HD) and attempts at reviewing its pharmacotherapy. It appears that after the newly founded diagnosis appeared in the literature as an autonomous entity, distinct from obsessive-compulsive disorder, drug trials are not being conducted and the disorder is left in the hands of psychotherapists, who on their part, report fair results in some core dimensions of HD. The few trials on HD specifically regard the serotonin-noradrenaline reuptake inhibitor venlafaxine, and, possibly due to the suggestion of a common biological background of HD with attention-deficit/hyperactivity disorder, the psychostimulant methylphenidate and the noradrenaline reuptake inhibitor atomoxetine. For all these drugs, positive results have been reported, but the evidence level of these studies is low, due to small samples and non-blind designs. Regretfully, there are currently no future studies aiming at seriously testing drugs in HD.
Identifiants
pubmed: 30678629
pii: CN-EPUB-96088
doi: 10.2174/1570159X17666190124153048
pmc: PMC7059160
doi:
Substances chimiques
Serotonin Uptake Inhibitors
0
Methylphenidate
207ZZ9QZ49
Atomoxetine Hydrochloride
57WVB6I2W0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
808-815Informations de copyright
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
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