Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation.
Animals
Biomarkers
/ metabolism
Encephalitis
Encephalomyelitis, Autoimmune, Experimental
/ pathology
Gene Expression Regulation
Genetic Loci
Inflammation
/ immunology
Lymphocyte Activation
/ immunology
Matrix Attachment Region Binding Proteins
/ metabolism
Mice, Inbred C57BL
Mice, Knockout
Programmed Cell Death 1 Receptor
/ metabolism
Promoter Regions, Genetic
/ genetics
Protein Binding
Spinal Cord
/ metabolism
Th17 Cells
/ immunology
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
01 02 2019
01 02 2019
Historique:
received:
30
04
2018
accepted:
07
01
2019
entrez:
3
2
2019
pubmed:
3
2
2019
medline:
2
4
2019
Statut:
epublish
Résumé
The genome organizer, special AT-rich sequence-binding protein-1 (Satb1), plays a pivotal role in the regulation of global gene networks in a cell type-dependent manner and is indispensable for the development of multiple cell types, including mature CD4
Identifiants
pubmed: 30710091
doi: 10.1038/s41467-019-08404-w
pii: 10.1038/s41467-019-08404-w
pmc: PMC6358604
doi:
Substances chimiques
Biomarkers
0
Matrix Attachment Region Binding Proteins
0
Programmed Cell Death 1 Receptor
0
Satb1 protein, mouse
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
549Références
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