A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart.
gene knockout
heart
macrophage
molecular motor
myosin
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
03 05 2019
03 05 2019
Historique:
received:
21
06
2018
revised:
19
01
2019
pubmed:
10
2
2019
medline:
8
1
2020
entrez:
10
2
2019
Statut:
ppublish
Résumé
Whereas myosin 18B (Myo18B) is known to be a critical sarcomeric protein, the function of myosin 18A (Myo18A) is unclear, although it has been implicated in cell motility and Golgi shape. Here, we show that homozygous deletion (homozygous tm1a, tm1b, or tm1d alleles) of
Identifiants
pubmed: 30737279
pii: S0021-9258(20)36799-5
doi: 10.1074/jbc.RA118.004560
pmc: PMC6509511
doi:
Substances chimiques
Myo18a protein, mouse
0
Protein Isoforms
0
enhanced green fluorescent protein
0
Green Fluorescent Proteins
147336-22-9
Myosins
EC 3.6.4.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
7202-7218Informations de copyright
© 2019 Horsthemke et al.
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