Autoantibodies to a specific peptide epitope of human Hsp60 (ATVLA) with homology to Helicobacter pylori HspB in H. pylori-infected patients.
Adult
Aged
Aged, 80 and over
Animals
Antibodies, Bacterial
/ blood
Autoantibodies
/ blood
Bacterial Proteins
/ chemistry
Cell Line
Chaperonin 60
/ chemistry
Cross Reactions
Cytokines
/ metabolism
Disease Models, Animal
Epitopes
/ chemistry
Female
Guinea Pigs
Heat-Shock Proteins
/ chemistry
Helicobacter Infections
/ immunology
Helicobacter pylori
/ immunology
Humans
Immunoglobulin G
/ blood
Male
Middle Aged
Mitochondrial Proteins
/ chemistry
Molecular Mimicry
/ immunology
Monocytes
/ metabolism
Helicobacter pylori
Antigenic mimicry
HspB
atherogenesis
gastritis
human Hsp60
Journal
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
ISSN: 1600-0463
Titre abrégé: APMIS
Pays: Denmark
ID NLM: 8803400
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
24
09
2018
accepted:
27
12
2018
entrez:
13
2
2019
pubmed:
13
2
2019
medline:
21
3
2019
Statut:
ppublish
Résumé
Helicobacter pylori (Hp) may initiate autoimmunity as a result of molecular mimicry. The aim of this study was to compare the level of IgG antibodies to a specific epitope (P1 peptide) of human heat shock protein (Hsp)60 homologous to Hp Hsp60 (HspB) in the sera of healthy donors (HD), patients with Hp-related gastritis or coronary heart disease (CHD), uninfected or with Hp infection confirmed by rapid urease test, histological examination (dyspeptic patients) the
Substances chimiques
Antibodies, Bacterial
0
Autoantibodies
0
Bacterial Proteins
0
Chaperonin 60
0
Cytokines
0
Epitopes
0
HSPD1 protein, human
0
Heat-Shock Proteins
0
HspB protein, Helicobacter pylori
0
Immunoglobulin G
0
Mitochondrial Proteins
0
Banques de données
GENBANK
['AAL86900.1']
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
139-149Subventions
Organisme : National Center of Science
ID : NCN 2015/17/N/NZ6/0349
Informations de copyright
© 2019 APMIS. Published by John Wiley & Sons Ltd.