Intratympanic steroid therapy for refractory sudden sensory hearing loss: a 12-year experience with the Silverstein catheter.
Adult
Audiometry, Pure-Tone
Databases, Factual
Dexamethasone
/ therapeutic use
Female
Hearing Loss, Sensorineural
/ diagnosis
Hearing Loss, Sudden
/ diagnosis
Hearing Tests
Humans
Injections, Intralesional
Male
Methylprednisolone
/ therapeutic use
Middle Aged
Prognosis
Reference Values
Retrospective Studies
Risk Assessment
Speech Intelligibility
/ drug effects
Statistics, Nonparametric
Treatment Outcome
Tympanic Membrane
/ drug effects
Idiopathic sudden sensorineural hearing loss
intratympanic therapy
steroid therapy
Journal
Acta oto-laryngologica
ISSN: 1651-2251
Titre abrégé: Acta Otolaryngol
Pays: England
ID NLM: 0370354
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
pubmed:
23
2
2019
medline:
14
8
2019
entrez:
23
2
2019
Statut:
ppublish
Résumé
Sudden sensorineural hearing loss (SSNHL) is commonly encountered in clinical practice. Determine if local administration of corticosteroids to the inner ear can improve hearing and speech intelligibility after the failure of conventional treatment for SSNHL loss when administered for 10 days after the onset of the hearing loss in a large cohort of 77 patients. A Silverstein MicroWick™ was placed under local anesthesia and endoscopic control in the round window niche, allowing self-administration of methylprednisolone twice daily for four weeks. An improvement of the pure tone average was shown in 31% of patients. Speech intelligibility improved significantly in 55% of the total cohort and in 34% of the population with a stable pure tone average. Among the 77 patients, 22% used a hearing aid. Only 14% of the patients were hearing-aid users in the group with an improvement in speech intelligibility as opposed to 31% in the failure group. Local administration of steroids to the inner ear through the round window route improves hearing and speech intelligibility in patients after failure of conventional therapy. The use of a hearing aid was reduced by 50% when speech intelligibility was improved.
Sections du résumé
BACKGROUND
BACKGROUND
Sudden sensorineural hearing loss (SSNHL) is commonly encountered in clinical practice.
AIM/OBJECTIVE
OBJECTIVE
Determine if local administration of corticosteroids to the inner ear can improve hearing and speech intelligibility after the failure of conventional treatment for SSNHL loss when administered for 10 days after the onset of the hearing loss in a large cohort of 77 patients.
MATERIALS AND METHODS
METHODS
A Silverstein MicroWick™ was placed under local anesthesia and endoscopic control in the round window niche, allowing self-administration of methylprednisolone twice daily for four weeks.
RESULTS
RESULTS
An improvement of the pure tone average was shown in 31% of patients. Speech intelligibility improved significantly in 55% of the total cohort and in 34% of the population with a stable pure tone average. Among the 77 patients, 22% used a hearing aid. Only 14% of the patients were hearing-aid users in the group with an improvement in speech intelligibility as opposed to 31% in the failure group.
CONCLUSION AND SIGNIFICANCE
CONCLUSIONS
Local administration of steroids to the inner ear through the round window route improves hearing and speech intelligibility in patients after failure of conventional therapy. The use of a hearing aid was reduced by 50% when speech intelligibility was improved.
Identifiants
pubmed: 30794063
doi: 10.1080/00016489.2018.1532107
doi:
Substances chimiques
Dexamethasone
7S5I7G3JQL
Methylprednisolone
X4W7ZR7023
Types de publication
Comparative Study
Journal Article
Langues
eng