Correlation of spirometry and body plethysmography during exercise-induced bronchial obstruction.


Journal

Respiratory medicine
ISSN: 1532-3064
Titre abrégé: Respir Med
Pays: England
ID NLM: 8908438

Informations de publication

Date de publication:
03 2019
Historique:
received: 12 11 2018
revised: 16 01 2019
accepted: 17 01 2019
entrez: 5 3 2019
pubmed: 5 3 2019
medline: 24 3 2020
Statut: ppublish

Résumé

The exercise challenge is the gold standard for diagnosing exercise-induced bronchoconstriction (EIB). Airway obstructions appear up to 30 min after the challenge, with a maximum decrease in spirometry and a maximum increase in airway resistance. There is evidence that changes in body plethysmography parameters are more sensitive to the exercise challenge and precede those in spirometry. To compare changes in body plethysmography and spirometry parameters after exercise challenges and to verify the cut-off values of sReff in EIB. In 82 subjects with suspected EIB, a total of 473 lung function tests were measured at baseline and at 5, 10, 15, and 30 min after exercise challenges at different stages of bronchial obstruction. The maximum changes in the body plethysmography parameter sReff significantly preceded the maximum changes in the spirometry parameter FEV The changes in sReff were more sensitive and better indicated lung impairment than did the changes in FEV

Sections du résumé

BACKGROUND
The exercise challenge is the gold standard for diagnosing exercise-induced bronchoconstriction (EIB). Airway obstructions appear up to 30 min after the challenge, with a maximum decrease in spirometry and a maximum increase in airway resistance. There is evidence that changes in body plethysmography parameters are more sensitive to the exercise challenge and precede those in spirometry.
PURPOSE
To compare changes in body plethysmography and spirometry parameters after exercise challenges and to verify the cut-off values of sReff in EIB.
PROCEDURES
In 82 subjects with suspected EIB, a total of 473 lung function tests were measured at baseline and at 5, 10, 15, and 30 min after exercise challenges at different stages of bronchial obstruction.
FINDINGS
The maximum changes in the body plethysmography parameter sReff significantly preceded the maximum changes in the spirometry parameter FEV
CONCLUSION
The changes in sReff were more sensitive and better indicated lung impairment than did the changes in FEV

Identifiants

pubmed: 30827475
pii: S0954-6111(19)30027-7
doi: 10.1016/j.rmed.2019.01.011
pii:
doi:

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

54-59

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Johannes Schulze (J)

Department for Children and Adolescents, Allergy, Pulmonology, and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Germany. Electronic address: johannes.schulze@kgu.de.

Hans-Jürgen Smith (HJ)

Research in Respiratory Diagnostics, Berlin, Germany. Electronic address: H.Smith@arcor.de.

Celine Eichhorn (C)

Department for Children and Adolescents, Allergy, Pulmonology, and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Germany. Electronic address: celine-eichhorn@gmx.de.

Emilia Salzmann-Manrique (E)

Department of Medicine, Institute of Biostatistics and Mathematical Modeling, University Hospital Frankfurt, Goethe University, Germany. Electronic address: Emilia.Salzmann@kgu.de.

Melanie Dreßler (M)

Department for Children and Adolescents, Allergy, Pulmonology, and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Germany. Electronic address: Melanie.Dressler@kgu.de.

Stefan Zielen (S)

Department for Children and Adolescents, Allergy, Pulmonology, and Cystic Fibrosis, University Hospital Frankfurt, Goethe University, Germany. Electronic address: Stefan.Zielen@kgu.de.

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