'Meiotic genes' are constitutively expressed in an asexual amoeba and are not necessarily involved in sexual reproduction.
Acanthamoeba
Muller's ratchet
RNA-seq
asexual reproduction
meiosis
polyploidy
Journal
Biology letters
ISSN: 1744-957X
Titre abrégé: Biol Lett
Pays: England
ID NLM: 101247722
Informations de publication
Date de publication:
29 03 2019
29 03 2019
Historique:
entrez:
7
3
2019
pubmed:
7
3
2019
medline:
18
12
2019
Statut:
ppublish
Résumé
The amoebae (and many other protists) have traditionally been considered as asexual organisms, but suspicion has been growing that these organisms are cryptically sexual or are at least related to sexual lineages. This contention is mainly based on genome studies in which the presence of 'meiotic genes' has been discovered. Using RNA-seq (next-generation shotgun sequencing, identifying and quantifying the RNA species in a sample), we have found that the entire repertoire of meiotic genes is expressed in exponentially growing Acanthamoeba and we argue that these so-called meiotic genes are involved in the related process of homologous recombination in this amoeba. We contend that they are only involved in meiosis in other organisms that indulge in sexual reproduction and that homologous recombination is important in asexual protists as a guard against the accumulation of mutations. We also suggest that asexual reproduction is the ancestral state.
Identifiants
pubmed: 30836881
doi: 10.1098/rsbl.2018.0871
pmc: PMC6451372
doi:
Banques de données
figshare
['10.6084/m9.figshare.c.4421564']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
20180871Subventions
Organisme : Medical Research Council
ID : MR/K001744/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/J004243/1
Pays : United Kingdom
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