Effects of Virgin Olive Oils Differing in Their Bioactive Compound Contents on Biomarkers of Oxidative Stress and Inflammation in Healthy Adults: A Randomized Double-Blind Controlled Trial.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
06 Mar 2019
Historique:
received: 10 01 2019
revised: 13 02 2019
accepted: 25 02 2019
entrez: 9 3 2019
pubmed: 9 3 2019
medline: 24 5 2019
Statut: epublish

Résumé

A regular consumption of virgin olive oil (VOO) is associated with a reduced risk of cardiovascular disease. We aimed to assess whether the raw intake of an optimized VOO (OVOO, 490 ppm of phenolic compounds and 86 ppm of triterpenes), and a functional olive oil (FOO, 487 ppm of phenolic compounds and enriched with 389 ppm of triterpenes) supplementation (30 mL per day) during three weeks would provide additional health benefits to those produced by a standard VOO (124 ppm of phenolic compounds and 86 ppm of triterpenes) on oxidative and inflammatory biomarkers. Fifty-one healthy adults participated in a randomized, crossover, and controlled study. Urinary 8-hidroxy-2'-deoxyguanosine, plasma interleukin-8 (IL-8), and tumor necrosis factor α (TNF- α) concentrations were lower after the intervention with the FOO than after the OVOO (

Identifiants

pubmed: 30845690
pii: nu11030561
doi: 10.3390/nu11030561
pmc: PMC6470869
pii:
doi:

Substances chimiques

Biomarkers 0
Inflammation Mediators 0
Olive Oil 0
Phenols 0
Triterpenes 0

Banques de données

ClinicalTrials.gov
['NCT02520739']

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Centre for Industrial Technological Development
ID : ITC-20131031

Références

Biochem Biophys Res Commun. 2000 Nov 30;278(3):797-9
pubmed: 11095986
J Nutr. 2001 Feb;131(2):231-4
pubmed: 11160538
Curr Pharm Des. 2001 Jul;7(10):933-50
pubmed: 11472248
Br J Nutr. 2002 Sep;88(3):225-34; discussion 223-4
pubmed: 12207832
Phytomedicine. 2003 Mar;10(2-3):115-21
pubmed: 12725563
Planta Med. 2003 May;69(5):472-4
pubmed: 12802735
Free Radic Res. 2004 Feb;38(2):105-22
pubmed: 15104204
Eur J Nutr. 2005 Mar;44(2):121-7
pubmed: 15309433
J Nutr. 2004 Sep;134(9):2314-21
pubmed: 15333722
Antioxid Redox Signal. 2005 Jan-Feb;7(1-2):221-35
pubmed: 15650410
Exp Toxicol Pathol. 2005 Jul;57 Suppl 1:161-9
pubmed: 16092724
Free Radic Biol Med. 2006 Feb 15;40(4):608-16
pubmed: 16458191
Free Radic Res. 2006 Mar;40(3):295-302
pubmed: 16484046
Br J Nutr. 2006 Apr;95(4):742-51
pubmed: 16571154
Nat Prod Rep. 2006 Jun;23(3):394-411
pubmed: 16741586
FASEB J. 2007 Jan;21(1):45-52
pubmed: 17110467
Biochem Int. 1991 Jul;24(5):981-90
pubmed: 1776961
Mol Nutr Food Res. 2007 Oct;51(10):1215-24
pubmed: 17879994
J Nutr. 2008 Aug;138(8):1411-6
pubmed: 18641183
J Nutr Biochem. 2010 Apr;21(4):290-6
pubmed: 19369055
Clin Nutr. 2010 Feb;29(1):31-7
pubmed: 19573960
Nutr Res Pract. 2010 Apr;4(2):142-8
pubmed: 20461203
Food Chem Toxicol. 2010 Oct;48(10):2885-90
pubmed: 20650302
Pharm Biol. 2011 Jan;49(1):78-85
pubmed: 20684747
J Agric Food Chem. 2011 Jan 12;59(1):121-30
pubmed: 21142067
Planta Med. 2011 Nov;77(17):1890-7
pubmed: 21830187
Eur J Pharmacol. 2011 Dec 15;672(1-3):169-74
pubmed: 21970807
Mol Nutr Food Res. 2012 Jul;56(7):1043-57
pubmed: 22760979
PLoS One. 2013;8(3):e59392
pubmed: 23527181
BMC Med. 2013 May 01;11:117
pubmed: 23635324
J Agric Food Chem. 2013 Dec 18;61(50):12173-82
pubmed: 24279741
Curr Med Chem. 2015;22(11):1414-25
pubmed: 25515513
Phytomedicine. 2015 Jun 1;22(6):631-40
pubmed: 26055128
J Nutr. 2015 Aug;145(8):1808-16
pubmed: 26136593
Br J Nutr. 2015 Apr;113 Suppl 2:S19-28
pubmed: 26148918
Br J Nutr. 2015 Apr;113 Suppl 2:S94-101
pubmed: 26148926
Nutrients. 2015 Sep 11;7(9):7651-75
pubmed: 26378571
Mol Nutr Food Res. 2016 Feb;60(2):399-409
pubmed: 26499467
Antioxid Redox Signal. 2016 Apr 1;24(10):548-55
pubmed: 26650622
J Agric Food Chem. 2016 Mar 9;64(9):1879-88
pubmed: 26889783
Eur J Nutr. 2017 Jun;56(4):1421-1432
pubmed: 26951205
Int J Mol Sci. 2016 May 31;17(6):
pubmed: 27258251
Mol Med Rep. 2016 Aug;14(2):1323-31
pubmed: 27315552
BMC Complement Altern Med. 2016 Oct 22;16(1):404
pubmed: 27770787
Adv Med. 2016;2016:9152732
pubmed: 27774507
Mediators Inflamm. 2017;2017:3674390
pubmed: 28484308
Int J Mol Sci. 2017 Jun 29;18(7):null
pubmed: 28661441
Endocr Metab Immune Disord Drug Targets. 2018;18(1):63-74
pubmed: 29165098
J Sci Food Agric. 2018 Oct;98(13):4837-4844
pubmed: 29574746
Nutrients. 2018 May 16;10(5):null
pubmed: 29772657
Phytomedicine. 2018 Nov 15;50:166-177
pubmed: 30466975
Antioxidants (Basel). 2018 Nov 22;7(12):null
pubmed: 30469520
J Lipid Res. 1986 Jan;27(1):114-20
pubmed: 3958609

Auteurs

Estefania Sanchez-Rodriguez (E)

Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Center, University of Granada, Parque Tecnológico de la Salud, Avenida del Conocimiento s/n, Armilla, 18016 Granada, Spain. estefaniasr@outlook.com.

Sara Biel-Glesson (S)

Fundación Pública Andaluza para la Investigación Biosanitaria de Andalucía Oriental "Alejandro Otero" (FIBAO), Avenida de Madrid 15, 18012 Granada, Spain. sbiel@fibao.es.

Jose R Fernandez-Navarro (JR)

Fundación Pública Andaluza para la Investigación Biosanitaria de Andalucía Oriental "Alejandro Otero" (FIBAO), Avenida de Madrid 15, 18012 Granada, Spain. estrategia@innofood.es.

Miguel A Calleja (MA)

Fundación Pública Andaluza para la Investigación Biosanitaria de Andalucía Oriental "Alejandro Otero" (FIBAO), Avenida de Madrid 15, 18012 Granada, Spain. mangel.calleja.sspa@juntadeandalucia.es.

Juan A Espejo-Calvo (JA)

Instituto para la Calidad y Seguridad Alimentaria (ICSA), Avenida de la Hispanidad 17, 18320 Santa Fe, Granada, Spain. jaespejo@hotmail.com.

Blas Gil-Extremera (B)

Department of Medicine, University of Granada, Avenida de la Investigación 11, Armilla, 18016 Granada, Spain. Blasgil@ugr.es.

Rafael de la Torre (R)

Integrative Pharmacology and Systems Neuroscience Research Group, IMIM (Hospital del Mar Research Institute), Universitat Pompeu Fabra (CEXS-UPF), Dr. Aiguader 88, 08003 Barcelona, Spain. rtorre@imim.es.
Spanish Biomedical Research Networking Centre, Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Monforte de Lemos 3-5, 28029 Madrid, Spain. rtorre@imim.es.

Montserrat Fito (M)

Spanish Biomedical Research Networking Centre, Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Monforte de Lemos 3-5, 28029 Madrid, Spain. mfito@imim.es.
Cardiovascular Risk and Nutrition Research Group, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain, Dr. Aiguader 88, 08003 Barcelona, Spain. mfito@imim.es.

Maria-Isabel Covas (MI)

Spanish Biomedical Research Networking Centre, Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Monforte de Lemos 3-5, 28029 Madrid, Spain. Maria.nuproas@gmail.com.
NUPROAS Handelsbolag, Nackã, Sweden, NUPROAS HB, Apartado de Correos 93, 17242 Girona, Spain. Maria.nuproas@gmail.com.

Pedro Vilchez (P)

Laboratorio CEM Europa S.L., Polígono Industrial "Cañada de la Fuente", Carretera Fuensanta, s/n, 23600 Martos, Jaén, Spain. pvilchez@cmeuropa.com.

Juan de Dios Alche (JD)

Department of Biochemistry, Cell and Molecular Biology of Plants, Estación Experimental del Zaidín (CSIC), Profesor Albareda 1, 18008 Granada, Spain. Juandedios.alche@eez.csic.es.

Emilio Martinez de Victoria (E)

Department of Physiology, Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Center, University of Granada, Parque Tecnológico de la Salud, Avenida del Conocimiento s/n, Armilla, 18100 Granada, Spain. emiliom@ugr.es.

Angel Gil (A)

Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Center, University of Granada, Parque Tecnológico de la Salud, Avenida del Conocimiento s/n, Armilla, 18016 Granada, Spain. agil@ugr.es.
Spanish Biomedical Research Networking Centre, Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Monforte de Lemos 3-5, 28029 Madrid, Spain. agil@ugr.es.
Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA). Complejo Hospitalario Universitario de Granada, 18014 Granada, Spain. agil@ugr.es.

Maria D Mesa (MD)

Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Center, University of Granada, Parque Tecnológico de la Salud, Avenida del Conocimiento s/n, Armilla, 18016 Granada, Spain. mdmesa@ugr.es.
Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA). Complejo Hospitalario Universitario de Granada, 18014 Granada, Spain. mdmesa@ugr.es.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH