Dynamic Changes in the Niche with N-Cadherin Revisited: The HSC "Niche Herein".

Bone Marrow Bone and Bones Cadherins Hematopoiesis Hematopoietic Stem Cells

Journal

Cell stem cell
ISSN: 1875-9777
Titre abrégé: Cell Stem Cell
Pays: United States
ID NLM: 101311472

Informations de publication

Date de publication:
07 03 2019
Historique:
entrez: 9 3 2019
pubmed: 9 3 2019
medline: 18 12 2019
Statut: ppublish

Résumé

Recently in Cell Reports, Zhao et al. report that chemo-resistant (reserve) hematopoietic stem cells (HSCs) are maintained in the endosteal niche under the influence of N-cadherin+ bone-lining cells (Zhao et al., 2019). These findings further indicate that niches for bone marrow HSCs may differ dynamically during physiological and stress hematopoiesis.

Identifiants

DOI: 10.1016/j.stem.2019.02.007 PMID: 30849365
pubmed: 30849365
pii: S1934-5909(19)30049-9
doi: 10.1016/j.stem.2019.02.007
pii:
doi:

Substances chimiques

Cadherins 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

355-356

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Ayako Nakamura-Ishizu (A)

Cancer Science Institute, National University of Singapore, 14 Medical Drive, MD6, 117599, Singapore; International Research Center for Medical Sciences, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto City 860-0811, Japan.

Toshio Suda (T)

Cancer Science Institute, National University of Singapore, 14 Medical Drive, MD6, 117599, Singapore; International Research Center for Medical Sciences, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto City 860-0811, Japan. Electronic address: sudato@keio.jp.

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Classifications MeSH

questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Moelle osseuse › Dynamic Changes in the Niche with N-Cadherin...
questionsmedicales.fr › Tissus › Tissu conjonctif › Os et tissu osseux › Dynamic Changes in the Niche with N-Cadherin...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Cadhérines › Dynamic Changes in the Niche with N-Cadherin...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hématopoïèse › Dynamic Changes in the Niche with N-Cadherin...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système hématopoïétique › Cellules de la moelle osseuse › Cellules souches hématopoïétiques › Dynamic Changes in the Niche with N-Cadherin...