Report from the 4th Cardiovascular Outcome Trial (CVOT) Summit of the Diabetes & Cardiovascular Disease (D&CVD) EASD Study Group.

Biomedical Research / methods Cardiology / methods Cardiovascular Diseases / diagnosis Clinical Trials as Topic / methods Cooperative Behavior Diabetes Mellitus / diagnosis Endocrinology / methods Humans Hypoglycemic Agents / adverse effects Interdisciplinary Communication Practice Guidelines as Topic Treatment Outcome
CARMELINA CVOT Cardiovascular risk DECLARE-TIMI 58 Diabetes Harmony Outcomes ODYSSEY OUTCOMES

Journal

Cardiovascular diabetology
ISSN: 1475-2840
Titre abrégé: Cardiovasc Diabetol
Pays: England
ID NLM: 101147637

Informations de publication

Date de publication:
11 03 2019
Historique:
received: 30 01 2019
accepted: 04 02 2019
entrez: 13 3 2019
pubmed: 13 3 2019
medline: 24 4 2019
Statut: epublish

Résumé

The 4th Cardiovascular Outcome Trial (CVOT) Summit of the Diabetes & Cardiovascular Disease (D&CVD) EASD Study Group was held in Munich on 25-26 October 2018. As in previous years, this summit served as a reference meeting for in-depth discussions on the topic of recently completed and presented CVOTs. This year, focus was placed on the CVOTs CARMELINA, DECLARE-TIMI 58 and Harmony Outcomes. Trial implications for diabetes management and the impact of the new ADA/EASD consensus statement treatment algorithm were highlighted for diabetologists, cardiologists, endocrinologists, nephrologists and general practitioners. Discussions evolved from CVOTs to additional therapy options for heart failure (ARNI), knowledge gained for adjunct therapy of type 1 diabetes and, on the occasion of the 10 year anniversary of the FDA's "Guidance for Industry: "should CVOTs be continued and/or modified?" The 5th Cardiovascular Outcome Trial Summit will be held in Munich on 24-25 October 2019 ( http://www.cvot.org ).

Identifiants

DOI: 10.1186/s12933-019-0822-4 PMID: 30857522 PMC: PMC6410488
pubmed: 30857522
doi: 10.1186/s12933-019-0822-4
pii: 10.1186/s12933-019-0822-4
pmc: PMC6410488
doi:

Substances chimiques

Hypoglycemic Agents 0

Types de publication

Congress

Langues

eng

Sous-ensembles de citation

IM

Pagination

30

Références

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Auteurs

Oliver Schnell (O)

Forschergruppe Diabetes e. V., Ingolstaedter Landstraße 1, Neuherberg, 85764, Munich, Germany. oliver.schnell@lrz.uni-muenchen.de.

Eberhard Standl (E)

Forschergruppe Diabetes e. V., Ingolstaedter Landstraße 1, Neuherberg, 85764, Munich, Germany.

Doina Catrinoiu (D)

Internal Medicine Department, Clinical County Emergency Hospital Constanta, Tomis Blvd. No. 145, 900591, Constanța, Romania.

Baruch Itzhak (B)

Clalit Health Services and Technion Faculty of Medicine, 3 Zivoni Street, Haifa, Israel.

Nebojsa Lalic (N)

Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Dr Subotica 13, Belgrade, 11000, Serbia.

Dario Rahelic (D)

Diabetes and Metabolic Disorders, Dubrava University Hospital, Avenija Gojka Šuška 6, 10000, Zagreb, Croatia.

Jan Skrha (J)

3rd Department of Internal Medicine, 1st Faculty of Medicine, Charles University, U Nemocnice 1, 128 08, Prague 2, Czech Republic.

Paul Valensi (P)

Department of Endocrinology Diabetology Nutrition, CINFO, CRNH-IdF, Jean VERDIER Hospital, Paris 13 University, Avenue du 14 Juillet, 93140, Bondy, France.

Antonio Ceriello (A)

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Centro de Investigación Biomedica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.
Department of Cardiovascular and Metabolic Diseases, IRCCS MultiMedica, Via Milanese 300, 20099, Sesto San Giovanni, MI, Italy.

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