Effective syntheses of 2',4'-BNA

5-Methylcytosine / chemistry Adenine / chemistry Bridged-Ring Compounds / chemistry Glycosylation Guanine / chemistry Nucleotides / chemistry Oligonucleotides / chemical synthesis Thymine Transition Temperature Ultraviolet Rays
Bridged nucleic acids Nucleotides Oligonucleotides Sugar modifications

Journal

Bioorganic & medicinal chemistry
ISSN: 1464-3391
Titre abrégé: Bioorg Med Chem
Pays: England
ID NLM: 9413298

Informations de publication

Date de publication:
15 04 2019
Historique:
received: 28 12 2018
revised: 15 02 2019
accepted: 16 02 2019
pubmed: 14 3 2019
medline: 13 3 2020
entrez: 14 3 2019
Statut: ppublish

Résumé

We efficiently synthesized 2'-O,4'-C-aminomethylene-bridged nucleic acid (2',4'-BNA

Identifiants

DOI: 10.1016/j.bmc.2019.02.034 PMID: 30862430
pubmed: 30862430
pii: S0968-0896(18)32116-3
doi: 10.1016/j.bmc.2019.02.034
pii:
doi:

Substances chimiques

2',4'-BNA(NC) 0
Bridged-Ring Compounds 0
Nucleotides 0
Oligonucleotides 0
Guanine 5Z93L87A1R
5-Methylcytosine 6R795CQT4H
Adenine JAC85A2161
Thymine QR26YLT7LT

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1728-1741

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Aki Fujisaka (A)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; Faculty of Pharmacy, Osaka Ohtani University, Nishikiori-Kita 3-11-1, Tondabayashi, Osaka 584-8540, Japan.

Yoshiyuki Hari (Y)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima 770-8514, Japan.

Hiroko Takuma (H)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.

S M Abdur Rahman (SMA)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; Department of Clinical Pharmacy & Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.

Haruhisa Yoshikawa (H)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; BNA Inc, 7-7-20 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.

Juanjuan Pang (J)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.

Takeshi Imanishi (T)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; BNA Inc, 7-7-20 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.

Satoshi Obika (S)

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: obika@phs.osaka-u.ac.jp.

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrimidines › Pyrimidinones › Cytosine › 5-Méthyl-cytosine › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Purines › Adénine › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Composés polycycliques › Composés pontés › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Métabolisme › Métabolisme glucidique › Glycosylation › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Purines › Purinones › Hypoxanthines › Guanine › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Polynucléotides › Oligonucléotides › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrimidines › Pyrimidinones › Uracile › Thymine › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Phénomènes physiques › Thermodynamique › Température de transition › Effective syntheses of 2',4'-BNA
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Lumière du soleil › Rayons ultraviolets › Effective syntheses of 2',4'-BNA