Effect of ASP2205 fumarate, a novel 5-HT

Animals Azepines Dose-Response Relationship, Drug Female Fumarates / pharmacology Pressure Quinolines Rats, Sprague-Dawley Reflex / drug effects Serotonin 5-HT2 Receptor Agonists / pharmacology Urethra / innervation Urinary Incontinence, Stress / prevention & control
5-HT(2C) receptor ASP2205 Leak point pressure Urethral closure response Urethral pressure

Journal

Journal of pharmacological sciences
ISSN: 1347-8648
Titre abrégé: J Pharmacol Sci
Pays: Japan
ID NLM: 101167001

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 15 01 2019
revised: 07 02 2019
accepted: 20 02 2019
pubmed: 16 3 2019
medline: 3 1 2020
entrez: 16 3 2019
Statut: ppublish

Résumé

The pharmacological profile of ASP2205 fumarate (ASP2205), a novel 5-HT

Identifiants

DOI: 10.1016/j.jphs.2019.02.004 PMID: 30871873
pubmed: 30871873
pii: S1347-8613(19)30024-6
doi: 10.1016/j.jphs.2019.02.004
pii:
doi:

Substances chimiques

ASP2205 0
Azepines 0
Fumarates 0
Quinolines 0
Serotonin 5-HT2 Receptor Agonists 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

333-339

Informations de copyright

Copyright © 2019 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

Auteurs

Takao Ishigami (T)

Institute for Drug Discovery Research, Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan. Electronic address: takao.ishigami@astellas.com.

Koji Ueshima (K)

Institute for Drug Discovery Research, Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.

Masashi Ukai (M)

Institute for Drug Discovery Research, Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.

Norio Asai (N)

Institute for Drug Discovery Research, Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.

Hajime Takamatsu (H)

Institute for Drug Discovery Research, Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.

Masanori Yokono (M)

Institute for Drug Discovery Research, Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.

Masahiro Takeda (M)

Institute for Drug Discovery Research, Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.

Noriyuki Masuda (N)

Institute for Drug Discovery Research, Astellas Pharma Inc, 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azépines › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Diacides carboxyliques › Fumarates › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Phénomènes physiques › Phénomènes mécaniques › Pression › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Sprague-Dawley › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Réflexe › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents sérotoninergiques › Agonistes des récepteurs de la sérotonine › Agonistes des récepteurs 5-HT2 de la sérotonine › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Urètre › Effect of ASP2205 fumarate, a novel 5-HT
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations urologiques › Symptômes de l'appareil urinaire inférieur › Incontinence urinaire › Incontinence urinaire d'effort › Effect of ASP2205 fumarate, a novel 5-HT