Systolic blood pressure on admission as a marker of fluid re-distribution in acute heart failure.
Acute Disease
Aged
Biomarkers
/ analysis
Blood Pressure
/ physiology
Blood Pressure Determination
Body Weight
/ physiology
Female
Heart Failure
/ physiopathology
Humans
Hydrodynamics
Male
Middle Aged
Patient Admission
/ statistics & numerical data
Pericardial Fluid
/ physiology
Prognosis
Regression Analysis
Acute heart failure
Blood pressure
Clinical scenario
Fluid re-distribution
Plasma volume
Journal
Journal of cardiology
ISSN: 1876-4738
Titre abrégé: J Cardiol
Pays: Netherlands
ID NLM: 8804703
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
25
12
2018
revised:
14
02
2019
accepted:
06
03
2019
pubmed:
8
4
2019
medline:
2
7
2020
entrez:
8
4
2019
Statut:
ppublish
Résumé
The relation between systolic blood pressure (sBP) on admission and the extent of fluid re-distribution in patients with acute heart failure (AHF) remains unclear. This study aimed to investigate this relation. We enrolled consecutive patients who were admitted for AHF in our cardiology department and divided them into three groups according to the tertiles of sBP on admission as follows: low, intermediate, and high sBP groups. Weight changes and estimated relative plasma volume changes (ΔePV) on admission and 24h later were determined in each patient. ΔePV were calculated with the Strauss formula using hemoglobin and hematocrit levels. Univariate and multiple regression analyses were performed to investigate the relation between sBP and ΔePV. The ΔePV of low, intermediate, and high sBP groups were 104.3%, 108.2%, and 121.3%, respectively. High sBP group showed a significantly larger ΔePV than the other two groups (p<0.001 and 0.004, respectively). The body weight of patients in the high sBP group slightly but significantly decreased within 24h (-0.64±0.92kg, p=0.002). The initial sBP had a significant correlation with ΔePV (R These results indicate that large amounts of extravasated fluid existed on admission in patients with a high initial sBP. The sBP on admission could be a simple and useful indicator for the extent of fluid re-distribution in AHF.
Sections du résumé
BACKGROUND
BACKGROUND
The relation between systolic blood pressure (sBP) on admission and the extent of fluid re-distribution in patients with acute heart failure (AHF) remains unclear. This study aimed to investigate this relation.
METHODS
METHODS
We enrolled consecutive patients who were admitted for AHF in our cardiology department and divided them into three groups according to the tertiles of sBP on admission as follows: low, intermediate, and high sBP groups. Weight changes and estimated relative plasma volume changes (ΔePV) on admission and 24h later were determined in each patient. ΔePV were calculated with the Strauss formula using hemoglobin and hematocrit levels. Univariate and multiple regression analyses were performed to investigate the relation between sBP and ΔePV.
RESULTS
RESULTS
The ΔePV of low, intermediate, and high sBP groups were 104.3%, 108.2%, and 121.3%, respectively. High sBP group showed a significantly larger ΔePV than the other two groups (p<0.001 and 0.004, respectively). The body weight of patients in the high sBP group slightly but significantly decreased within 24h (-0.64±0.92kg, p=0.002). The initial sBP had a significant correlation with ΔePV (R
CONCLUSIONS
CONCLUSIONS
These results indicate that large amounts of extravasated fluid existed on admission in patients with a high initial sBP. The sBP on admission could be a simple and useful indicator for the extent of fluid re-distribution in AHF.
Identifiants
pubmed: 30954380
pii: S0914-5087(19)30063-2
doi: 10.1016/j.jjcc.2019.03.003
pii:
doi:
Substances chimiques
Biomarkers
0
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
245-250Informations de copyright
Copyright © 2019 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.