[Anti-laminin 332 mucous membrane pemphigoid with irreversible ocular and tracheobronchial involvement : Delayed diagnosis of a severe autoimmune bullous disease].

Anti-Laminin-332-Schleimhautpemphigoid mit irreversiblem okulärem und tracheobronchialem Befall : Verspätete Diagnosestellung einer schweren bullösen Autoimmunerkrankung.

Journal

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
ISSN: 1432-1173
Titre abrégé: Hautarzt
Pays: Germany
ID NLM: 0372755

Informations de publication

Date de publication:
May 2019
Historique:
pubmed: 10 4 2019
medline: 8 10 2019
entrez: 10 4 2019
Statut: ppublish

Résumé

A 53-year-old man presented with a 37-year history of erosive and scarring mucosal lesions of several organs. An initial diagnosis of Stevens-Johnson syndrome was maintained for many years. Due to late correct diagnosis of an anti-laminin 332 mucous membrane pemphigoid and the fact that early, targeted, intensified immunosuppressive therapy was not initiated, the disease led to almost complete loss of vision and obstruction of airways.

Identifiants

pubmed: 30963224
doi: 10.1007/s00105-019-4402-z
pii: 10.1007/s00105-019-4402-z
doi:

Substances chimiques

Autoantibodies 0
Cell Adhesion Molecules 0

Types de publication

Case Reports Journal Article

Langues

ger

Sous-ensembles de citation

IM

Pagination

367-370

Références

Lancet. 2001 Jun 9;357(9271):1850-1
pubmed: 11410196
Int Immunopharmacol. 2016 May;34:25-31
pubmed: 26919279
J Invest Dermatol. 2016 Dec;136(12):2495-2498
pubmed: 27456755
Cutis. 2016 Sep;98(3):E24-E27
pubmed: 27814419
Hautarzt. 2018 Jan;69(1):67-83
pubmed: 29242962

Auteurs

F M Syring (FM)

Klinik für Dermatologie, Allergologie und Venerologie, Universität Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland. felicia.syring@uksh.de.

D Zillikens (D)

Klinik für Dermatologie, Allergologie und Venerologie, Universität Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

E Schmidt (E)

Klinik für Dermatologie, Allergologie und Venerologie, Universität Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

M Kasperkiewicz (M)

Klinik für Dermatologie, Allergologie und Venerologie, Universität Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

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Classifications MeSH