Mutations in the zebrafish
Amino Acid Substitution
Animals
Cell Differentiation
/ genetics
Cholesterol
/ biosynthesis
Erythrocytes
/ enzymology
Erythropoiesis
/ genetics
GATA1 Transcription Factor
/ biosynthesis
Gene Expression Regulation
Hydroxymethylglutaryl-CoA Synthase
/ genetics
Mutation, Missense
Terpenes
/ metabolism
Zebrafish
/ genetics
Zebrafish Proteins
/ biosynthesis
Journal
Blood advances
ISSN: 2473-9537
Titre abrégé: Blood Adv
Pays: United States
ID NLM: 101698425
Informations de publication
Date de publication:
23 04 2019
23 04 2019
Historique:
received:
09
08
2018
accepted:
09
03
2019
entrez:
17
4
2019
pubmed:
17
4
2019
medline:
15
5
2020
Statut:
ppublish
Résumé
Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or thalassemia. The GATA1 transcription factor is an established mediator of RBC development. However, the upstream mechanisms that regulate the expression of
Identifiants
pubmed: 30987969
pii: bloodadvances.2018024539
doi: 10.1182/bloodadvances.2018024539
pmc: PMC6482358
doi:
Substances chimiques
GATA1 Transcription Factor
0
Terpenes
0
Zebrafish Proteins
0
gata1a protein, zebrafish
0
Cholesterol
97C5T2UQ7J
Hydroxymethylglutaryl-CoA Synthase
EC 2.3.3.10
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1244-1254Subventions
Organisme : NINDS NIH HHS
ID : K01 NS099153
Pays : United States
Organisme : NIGMS NIH HHS
ID : R25 GM069621
Pays : United States
Organisme : NIGMS NIH HHS
ID : RL5 GM118969
Pays : United States
Organisme : NIGMS NIH HHS
ID : UL1 GM118970
Pays : United States
Organisme : NIGMS NIH HHS
ID : TL4 GM118971
Pays : United States
Organisme : NIMHD NIH HHS
ID : G12 MD007592
Pays : United States
Informations de copyright
© 2019 by The American Society of Hematology.
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