A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity.


Journal

Nature genetics
ISSN: 1546-1718
Titre abrégé: Nat Genet
Pays: United States
ID NLM: 9216904

Informations de publication

Date de publication:
05 2019
Historique:
received: 11 06 2018
accepted: 28 02 2019
pubmed: 17 4 2019
medline: 14 6 2019
entrez: 17 4 2019
Statut: ppublish

Résumé

BMP/SMAD signaling is a crucial regulator of intestinal differentiation

Identifiants

pubmed: 30988513
doi: 10.1038/s41588-019-0384-0
pii: 10.1038/s41588-019-0384-0
pmc: PMC6650150
mid: NIHMS1522942
doi:

Substances chimiques

HNF4A protein, human 0
HNF4G protein, human 0
Hepatocyte Nuclear Factor 4 0
Hnf4a protein, mouse 0
Hnf4g protein, mouse 0
SMAD4 protein, human 0
Smad4 Protein 0
Smad4 protein, mouse 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

777-785

Subventions

Organisme : NCI NIH HHS
ID : P30 CA072720
Pays : United States
Organisme : NIDDK NIH HHS
ID : U24 DK085532
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK103141
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK085532
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA190558
Pays : United States

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Auteurs

Lei Chen (L)

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.
Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.

Natalie H Toke (NH)

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.

Shirley Luo (S)

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.

Roshan P Vasoya (RP)

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.

Robert L Fullem (RL)

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.

Aditya Parthasarathy (A)

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.

Ansu O Perekatt (AO)

Department of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, NJ, USA.

Michael P Verzi (MP)

Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA. verzi@biology.rutgers.edu.
Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA. verzi@biology.rutgers.edu.

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Classifications MeSH