Machine learning and big data in psychiatry: toward clinical applications.


Journal

Current opinion in neurobiology
ISSN: 1873-6882
Titre abrégé: Curr Opin Neurobiol
Pays: England
ID NLM: 9111376

Informations de publication

Date de publication:
04 2019
Historique:
received: 11 06 2018
revised: 29 01 2019
accepted: 07 02 2019
pubmed: 19 4 2019
medline: 11 2 2020
entrez: 19 4 2019
Statut: ppublish

Résumé

Psychiatry is a medical field concerned with the treatment of mental illness. Psychiatric disorders broadly relate to higher functions of the brain, and as such are richly intertwined with social, cultural, and experiential factors. This makes them exquisitely complex phenomena that depend on and interact with a large number of variables. Computational psychiatry provides two ways of approaching this complexity. Theory-driven computational approaches employ mechanistic models to make explicit hypotheses at multiple levels of analysis. Data-driven machine-learning approaches can make predictions from high-dimensional data and are generally agnostic as to the underlying mechanisms. Here, we review recent advances in the use of big data and machine-learning approaches toward the aim of alleviating the suffering that arises from psychiatric disorders.

Identifiants

pubmed: 30999271
pii: S0959-4388(18)30089-8
doi: 10.1016/j.conb.2019.02.006
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

152-159

Subventions

Organisme : Medical Research Council
ID : MR/N02401X/1
Pays : United Kingdom
Organisme : Department of Health
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 203147/Z/16/Z
Pays : United Kingdom

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Robb B Rutledge (RB)

Max Planck UCL Centre for Computational Psychiatry and Ageing Research, University College London, London, England, United Kingdom; Wellcome Centre for Human Neuroimaging, University College London, London, England, United Kingdom.

Adam M Chekroud (AM)

Department of Psychiatry, Yale University, New Haven, CT, United States; Spring Health, New York, NY, United States.

Quentin Jm Huys (QJ)

Max Planck UCL Centre for Computational Psychiatry and Ageing Research, University College London, London, England, United Kingdom; Division of Psychiatry, University College London, London, England, United Kingdom; Camden and Islington NHS Foundation Trust, London, England, United Kingdom. Electronic address: qhuys@cantab.net.

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Classifications MeSH