Blood profile of atrophic glossitis patients with thyroglobulin antibody/thyroid microsomal antibody positivity but without gastric parietal cell antibody positivity.
Atrophic glossitis
Folic acid deficiency
Hyperhomocysteinemia
Iron deficiency
Thyroglobulin antibody
Thyroid microsomal antibody
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
ISSN: 0929-6646
Titre abrégé: J Formos Med Assoc
Pays: Singapore
ID NLM: 9214933
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
27
03
2019
accepted:
02
04
2019
pubmed:
22
4
2019
medline:
16
1
2020
entrez:
22
4
2019
Statut:
ppublish
Résumé
Our previous study found that 304 of 1064 atrophic glossitis (AG) patients have thyroglobulin antibody (TGA) positivity and/or thyroid microsomal antibody (TMA) positivity but without gastric parietal cell antibody positivity (GPCA־TGA The mean blood hemoglobin (Hb), iron, vitamin B12, folic acid, and homocysteine levels were measured and compared between 304 GPCA־TGA We found significantly lower MCV and lower mean blood Hb and iron levels as well as significantly greater frquencies of microcytosis, macrocytosis, blood Hb, iron, vitamin B12, and folic acid deficiencies and hyperhomocysteinemia in 304 GPCA־TGA The disease of AG itself plays a significant role in causing anemia, hematinic deficiencies, and hyperhomocysteinemia in GPCA־TGA
Sections du résumé
BACKGROUND/PURPOSE
OBJECTIVE
Our previous study found that 304 of 1064 atrophic glossitis (AG) patients have thyroglobulin antibody (TGA) positivity and/or thyroid microsomal antibody (TMA) positivity but without gastric parietal cell antibody positivity (GPCA־TGA
METHODS
METHODS
The mean blood hemoglobin (Hb), iron, vitamin B12, folic acid, and homocysteine levels were measured and compared between 304 GPCA־TGA
RESULTS
RESULTS
We found significantly lower MCV and lower mean blood Hb and iron levels as well as significantly greater frquencies of microcytosis, macrocytosis, blood Hb, iron, vitamin B12, and folic acid deficiencies and hyperhomocysteinemia in 304 GPCA־TGA
CONCLUSION
CONCLUSIONS
The disease of AG itself plays a significant role in causing anemia, hematinic deficiencies, and hyperhomocysteinemia in GPCA־TGA
Identifiants
pubmed: 31005374
pii: S0929-6646(19)30268-2
doi: 10.1016/j.jfma.2019.04.002
pii:
doi:
Substances chimiques
Autoantibodies
0
Hemoglobins
0
Folic Acid
935E97BOY8
Iron
E1UOL152H7
Vitamin B 12
P6YC3EG204
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1218-1224Informations de copyright
Copyright © 2019 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.