Mutations in


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
14 05 2019
Historique:
pubmed: 1 5 2019
medline: 27 3 2020
entrez: 1 5 2019
Statut: ppublish

Résumé

Congenital disorders of glycosylation (CDG) are a group of rare metabolic diseases, due to impaired protein and lipid glycosylation. We identified two patients with defective serum transferrin glycosylation and mutations in the

Identifiants

pubmed: 31036665
pii: 1817815116
doi: 10.1073/pnas.1817815116
pmc: PMC6525510
doi:

Substances chimiques

Cation Transport Proteins 0
MagT1 protein, human 0
Membrane Proteins 0
TUSC3 protein, human 0
Tumor Suppressor Proteins 0
Hexosyltransferases EC 2.4.1.-
STT3B protein, human EC 2.4.99.18

Types de publication

Case Reports Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9865-9870

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM043768
Pays : United States

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

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Auteurs

Eline Blommaert (E)

Laboratory for Molecular Diagnosis, Center for Human Genetics, KU Leuven, 3000 Leuven, Belgium.

Romain Péanne (R)

Laboratory for Molecular Diagnosis, Center for Human Genetics, KU Leuven, 3000 Leuven, Belgium.

Natalia A Cherepanova (NA)

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655.

Daisy Rymen (D)

Division of Metabolic Diseases, University Children's Hospital, 8032 Zürich, Switzerland.

Frederik Staels (F)

KU Leuven Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Group, KU Leuven, 3000 Leuven, Belgium.

Jaak Jaeken (J)

Department of Pediatrics, Center for Metabolic Diseases, KU Leuven, 3000 Leuven, Belgium.

Valérie Race (V)

Laboratory for Molecular Diagnosis, Center for Human Genetics, KU Leuven, 3000 Leuven, Belgium.

Liesbeth Keldermans (L)

Laboratory for Molecular Diagnosis, Center for Human Genetics, KU Leuven, 3000 Leuven, Belgium.

Erika Souche (E)

Laboratory for Molecular Diagnosis, Center for Human Genetics, KU Leuven, 3000 Leuven, Belgium.

Anniek Corveleyn (A)

Laboratory for Molecular Diagnosis, Center for Human Genetics, KU Leuven, 3000 Leuven, Belgium.

Rebecca Sparkes (R)

Alberta Children's Hospital, Calgary, AB T3B 6A8, Canada.

Kaustuv Bhattacharya (K)

Genetic Metabolic Disorders Service, Children's Hospital Westmead Clinical School, University of Sydney, NSW 2145 Westmead, Australia.

Christine Devalck (C)

Department of Hemato-Oncology, Hôpital Universitaire Des Enfants Reine Fabiola, Université Libre de Bruxelles, 1020 Brussels, Belgium.

Rik Schrijvers (R)

KU Leuven Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Group, KU Leuven, 3000 Leuven, Belgium.

François Foulquier (F)

Unité de Glycobiologie Structurale et Fonctionnelle, University Lille, CNRS, UMR 8576, F-59000 Lille, France.

Reid Gilmore (R)

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655.

Gert Matthijs (G)

Laboratory for Molecular Diagnosis, Center for Human Genetics, KU Leuven, 3000 Leuven, Belgium; gert.matthijs@kuleuven.be.

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Classifications MeSH