RACHS - ANZ : A Modified Risk Adjustment in Congenital Heart Surgery Model for Outcome Surveillance in Australia and New Zealand.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
07 05 2019
Historique:
entrez: 2 5 2019
pubmed: 2 5 2019
medline: 4 8 2020
Statut: ppublish

Résumé

Background Outcomes for pediatric cardiac surgery are commonly reported from international databases compiled from voluntary data submissions. Surgical outcomes for all children in a country or region are less commonly reported. We aimed to describe the bi-national population-based outcome for children undergoing cardiac surgery in Australia and New Zealand and determine whether the Risk Adjustment for Congenital Heart Surgery ( RACHS ) classification could be used to create a model that accurately predicts in-hospital mortality in this population. Methods and Results The study was conducted in all children's hospitals performing cardiac surgery in Australia and New Zealand between January 2007 and December 2015. The performance of the original RACHS -1 model was assessed and compared with an alternative RACHS - ANZ (Australia and New Zealand) model, developed balancing discrimination with parsimonious variable selection. A total of 14 324 hospital admissions were analyzed. The overall hospital mortality was 2.3%, ranging from 0.5% for RACHS category 1 procedures, to 17.0% for RACHS category 5 or 6 procedures. The original RACHS -1 model was poorly calibrated with death overpredicted (1161 deaths predicted, 289 deaths observed). The RACHS - ANZ model had better performance in this population with excellent discrimination (Az- ROC of 0.830) and acceptable Hosmer and Lemeshow goodness-of-fit ( P=0.216). Conclusions The original RACHS -1 model overpredicts mortality in children undergoing heart surgery in the current era. The RACHS - ANZ model requires only 3 risk variables in addition to the RACHS procedure category, can be applied to a wider range of patients than RACHS -1, and is suitable to use to monitor regional pediatric cardiac surgery outcomes.

Identifiants

pubmed: 31039662
doi: 10.1161/JAHA.118.011390
pmc: PMC6512128
doi:

Types de publication

Journal Article Multicenter Study Research Support, Non-U.S. Gov't Validation Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

e011390

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Auteurs

Brent McSharry (B)

1 Paediatric Intensive Care Unit Starship Children's Hospital Auckland New Zealand.

Lahn Straney (L)

3 Department of Epidemiology and Preventive Medicine Monash University Melbourne Australia.

Janet Alexander (J)

4 Australian and New Zealand Intensive Care Society Melbourne Australia.

Tom Gentles (T)

2 Green Lane Paediatric and Congenital Cardiac Service Starship Children's Hospital Auckland New Zealand.

David Winlaw (D)

5 Heart Centre for Children The Children's Hospital Westmead Sydney Australia.
7 School of Medicine University of Sydney Australia.

John Beca (J)

1 Paediatric Intensive Care Unit Starship Children's Hospital Auckland New Zealand.

Johnny Millar (J)

8 Intensive Care Unit Royal Children's Hospital Melbourne Australia.
9 Department of Paediatrics University of Melbourne Australia.

Frank Shann (F)

8 Intensive Care Unit Royal Children's Hospital Melbourne Australia.
9 Department of Paediatrics University of Melbourne Australia.

Barry Wilkins (B)

6 Paediatric Intensive Care Unit The Children's Hospital Westmead Sydney Australia.

Andrew Numa (A)

10 Paediatric Intensive Care Unit Sydney Children's Hospital Sydney Australia.

Christian Stocker (C)

11 Paediatric Intensive Care Unit Queensland Children's Hospital Brisbane Australia.

Simon Erickson (S)

12 Paediatric Intensive Care Unit Perth Children's Hospital Perth Australia.

Anthony Slater (A)

11 Paediatric Intensive Care Unit Queensland Children's Hospital Brisbane Australia.

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