Multilayer intraclonal heterogeneity in chronic myelomonocytic leukemia.
Journal
Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
04
10
2018
accepted:
30
04
2019
pubmed:
3
5
2019
medline:
28
4
2021
entrez:
4
5
2019
Statut:
ppublish
Résumé
The functional diversity of cells that compose myeloid malignancies, i.e., the respective roles of genetic and epigenetic heterogeneity in this diversity, remains poorly understood. This question is addressed in chronic myelomonocytic leukemia, a myeloid neoplasm in which clinical diversity contrasts with limited genetic heterogeneity. To generate induced pluripotent stem cell clones, we reprogrammed CD34
Identifiants
pubmed: 31048357
pii: haematol.2018.208488
doi: 10.3324/haematol.2018.208488
pmc: PMC6939510
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
112-123Subventions
Organisme : NCI NIH HHS
ID : P30 CA240139
Pays : United States
Informations de copyright
Copyright© 2020 Ferrata Storti Foundation.
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