Non-curative treatment of patients with oral tongue squamous-cell carcinoma.
Chemotherapy
Death
End of life
Head and neck cancer
Palliation
Palliative care
Quality of life
Surgery
Tongue cancer
Journal
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
ISSN: 1434-4726
Titre abrégé: Eur Arch Otorhinolaryngol
Pays: Germany
ID NLM: 9002937
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
24
03
2019
accepted:
27
04
2019
pubmed:
10
5
2019
medline:
6
8
2019
entrez:
10
5
2019
Statut:
ppublish
Résumé
Late-stage OTSCC is associated with poor overall survival (OS). Non-curative treatment approach aims to improve quality of life and prolong survival of patients deemed incurable. The purpose of this study was to investigate the used non-curative treatment modalities for OTSSC and patient survival. All patients diagnosed with OTSCC and treated with non-curative intent at the HUS Helsinki University Hospital (Helsinki, Finland) during the 12-year period of 2005-2016 were included. Survival analysis after the non-curative treatment decision was conducted using the Kaplan-Meier method in this population-based study. Eighty-two patients were identified. A non-curative treatment decision was made at presentation without any previous treatment in 26 patients (7% of all patients diagnosed with OTSCC during the study period). Palliative radiotherapy was administered to 24% of all patients. The average survival time after the non-curative treatment decision was 3.7 months (median 2 and range 0-26). Due to the short mean survival time after decision for treatment with non-curative intent, and the notable symptom burden in this patient population, a prompt initiation of all non-curative measures is warranted.
Identifiants
pubmed: 31069467
doi: 10.1007/s00405-019-05456-y
pii: 10.1007/s00405-019-05456-y
pmc: PMC6581924
doi:
Types de publication
Journal Article
Langues
eng
Pagination
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