Synthesis, antimicrobial and antiproliferative properties of epi-oligomycin A, the (33

Animals Anti-Bacterial Agents / chemistry Antibiotics, Antineoplastic / chemistry Aspergillus niger / drug effects Candida / drug effects Cell Proliferation / drug effects Dogs Drug Resistance, Neoplasm Humans K562 Cells MCF-7 Cells Madin Darby Canine Kidney Cells Magnetic Resonance Spectroscopy Mass Spectrometry Microbial Sensitivity Tests Oligomycins / chemical synthesis Stereoisomerism Streptomyces / drug effects Structure-Activity Relationship
(33S)-oligomycin A 33-O-mesyloligomycin Oligomycin A antimicrobial activity cytotoxicity epimers mitochondrial F1FO ATP-synthase

Journal

Natural product research
ISSN: 1478-6427
Titre abrégé: Nat Prod Res
Pays: England
ID NLM: 101167924

Informations de publication

Date de publication:
Nov 2020
Historique:
pubmed: 12 5 2019
medline: 26 11 2020
entrez: 12 5 2019
Statut: ppublish

Résumé

We describe the synthesis of epi-oligomycin A, a (33

Identifiants

DOI: 10.1080/14786419.2019.1608540 PMID: 31075992
pubmed: 31075992
doi: 10.1080/14786419.2019.1608540
doi:

Substances chimiques

Anti-Bacterial Agents 0
Antibiotics, Antineoplastic 0
Oligomycins 0
oligomycin A 05HQS4AI99

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3073-3081

Auteurs

Lyudmila N Lysenkova (LN)

Gause Institute of New Antibiotics, Moscow, 119021, Russian Federation.

Oleg Y Saveljev (OY)

Lomonosov Moscow State University, Moscow, 119991, Russian Federation.

Olga A Omelchuk (OA)

Gause Institute of New Antibiotics, Moscow, 119021, Russian Federation.
Mendeleev University of Chemical Technology, Moscow, Russian Federation.

George V Zatonsky (GV)

Gause Institute of New Antibiotics, Moscow, 119021, Russian Federation.

Alexander M Korolev (AM)

Gause Institute of New Antibiotics, Moscow, 119021, Russian Federation.

Natalya E Grammatikova (NE)

Gause Institute of New Antibiotics, Moscow, 119021, Russian Federation.

Olga B Bekker (OB)

Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russian Federation.

Valery N Danilenko (VN)

Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russian Federation.

Lyubov G Dezhenkova (LG)

Gause Institute of New Antibiotics, Moscow, 119021, Russian Federation.

Dilara A Mavletova (DA)

Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russian Federation.

Alexander M Scherbakov (AM)

Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation.
ORCID: 0000-0002-2974-9555

Andrey E Shchekotikhin (AE)

Gause Institute of New Antibiotics, Moscow, 119021, Russian Federation.
Mendeleev University of Chemical Technology, Moscow, Russian Federation.
ORCID: 0000-0002-6595-0811

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Antibiotiques antinéoplasiques › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Eucaryotes › Champignons › Deuteromycota › Aspergillus › Aspergillus niger › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Candida › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Carnivora › Pinnipedia › Canidae › Chiens › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance aux médicaments antinéoplasiques › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Cellules › Cellules érythroïdes › Cellules K562 › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Cellules MCF-7 › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules rénales canines Madin-Darby › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Composés chimiques organiques › Lactones › Oligomycines › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes de chimie organique › Isomérie › Stéréoisomérie › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets sporulés à Gram positif › Streptomycetaceae › Streptomyces › Synthesis, antimicrobial and antiproliferative...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Synthesis, antimicrobial and antiproliferative...