Prevalence of gastroesophageal reflux and risk factors for erosive esophagitis in obese patients considered for bariatric surgery.
Adult
Cross-Sectional Studies
Endoscopy, Digestive System
/ adverse effects
Esophagitis, Peptic
/ epidemiology
Female
Gastric Bypass
Gastroesophageal Reflux
/ epidemiology
Hernia, Hiatal
/ complications
Humans
Lebanon
/ epidemiology
Logistic Models
Male
Middle Aged
Multivariate Analysis
Obesity
/ complications
Postoperative Complications
/ epidemiology
Prevalence
Prospective Studies
Proton Pump Inhibitors
/ adverse effects
Risk Factors
Sensitivity and Specificity
Acid
Endoscopy
Gastric bypass
Proton pump inhibitor
Sleeve gastrectomy
Journal
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
ISSN: 1878-3562
Titre abrégé: Dig Liver Dis
Pays: Netherlands
ID NLM: 100958385
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
received:
03
12
2018
revised:
05
04
2019
accepted:
10
04
2019
pubmed:
12
5
2019
medline:
1
5
2020
entrez:
12
5
2019
Statut:
ppublish
Résumé
Gastroesophageal reflux disease (GERD) is common in obese individuals. Prospective studies investigating validated GERD questionnaires and clinical parameters at identifying erosive esophagitis (EE) in this population are limited. To prospectively evaluate the prevalence of GERD in obese patients considered for bariatric surgery and identify risk and predictive factors for EE. Eligible patients completed two validated questionnaires: GERDQ and Nocturnal Symptom Severity Impact (N-GSSIQ) before routine esophagogastroduodenoscopy. 242 consecutive patients were enrolled (130 females; mean age 37.8 ± 11.8 years; mean BMI 40.4 ± 5.3 kg/m GERD is highly prevalent in obese patients. Anthropometric data and GERD questionnaires have limited accuracy at predicting erosive disease. Pre-operative endoscopic assessment in this population appears warranted.
Sections du résumé
BACKGROUND
Gastroesophageal reflux disease (GERD) is common in obese individuals. Prospective studies investigating validated GERD questionnaires and clinical parameters at identifying erosive esophagitis (EE) in this population are limited.
OBJECTIVE
To prospectively evaluate the prevalence of GERD in obese patients considered for bariatric surgery and identify risk and predictive factors for EE.
METHODS
Eligible patients completed two validated questionnaires: GERDQ and Nocturnal Symptom Severity Impact (N-GSSIQ) before routine esophagogastroduodenoscopy.
RESULTS
242 consecutive patients were enrolled (130 females; mean age 37.8 ± 11.8 years; mean BMI 40.4 ± 5.3 kg/m
CONCLUSION
GERD is highly prevalent in obese patients. Anthropometric data and GERD questionnaires have limited accuracy at predicting erosive disease. Pre-operative endoscopic assessment in this population appears warranted.
Identifiants
pubmed: 31076325
pii: S1590-8658(19)30550-X
doi: 10.1016/j.dld.2019.04.010
pii:
doi:
Substances chimiques
Proton Pump Inhibitors
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1375-1379Informations de copyright
Copyright © 2019 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.