Characterization of hepatitis delta virus strains spreading in Abuja, Nigeria.
blood
epidemiology
hepatitis B virus
hepatitis D virus
satellite
subviral agents
virus classification
Journal
Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876
Informations de publication
Date de publication:
09 2019
09 2019
Historique:
received:
22
01
2019
revised:
20
03
2019
accepted:
06
05
2019
pubmed:
14
5
2019
medline:
4
6
2020
entrez:
14
5
2019
Statut:
ppublish
Résumé
Hepatitis delta virus (HDV) is responsible for the most severe form of liver disease in humans. So far, eight genotypes (HDV-1 to -8) have been individualized worldwide. Little is known about HDV strains that spread in Nigeria. HDV genotyping was performed in 15 anti-HDV positive samples from a cohort of 306 hepatitis B virus (HBV)-infected patients in Abuja (Nigeria). Phylogenetic analyses revealed 90% were HDV-1, two among them clustering with European/Asian HDV-1, the remaining one being HDV-6. It was also found that two members of a couple superinfected with the same HDV strain, were enveloped by two different HBV strains of genotype E.
Substances chimiques
Hepatitis Antibodies
0
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1688-1692Informations de copyright
© 2019 Wiley Periodicals, Inc.