Early Postoperative Complications in Meningioma: Predictive Factors and Impact on Outcome.
Adult
Age Factors
Aged
Aged, 80 and over
Brain Neoplasms
/ surgery
Cohort Studies
Craniotomy
/ adverse effects
Female
Follow-Up Studies
Humans
Male
Meningioma
/ surgery
Middle Aged
Neurosurgical Procedures
/ adverse effects
Norway
/ epidemiology
Postoperative Complications
/ epidemiology
Predictive Value of Tests
Quality of Life
Retrospective Studies
Risk Factors
Treatment Outcome
Young Adult
Complications
Meningioma
Outcome
Predictive factors
Recursive partitioning analysis
Journal
World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
21
01
2019
revised:
01
05
2019
accepted:
02
05
2019
pubmed:
15
5
2019
medline:
21
1
2020
entrez:
15
5
2019
Statut:
ppublish
Résumé
Craniotomies carry inherent risks of postoperative complications that may have a negative impact on patients' status. Recognizing and preventing surgical complications is of paramount importance, especially in meningioma surgery, where most of these tumors are benign and current management protocols are effective in terms of disease control and maintenance of higher quality of life. The objective of this study was to describe the early complications after surgery and their predictive factors in patients undergoing resection of intracranial meningiomas. A partly retrospective, partly prospective review was conducted in a Norwegian population-based cohort of 1469 consecutive cases of meningioma surgery treated at the university hospitals of Oslo, totaling 11,414 patient-years of follow-up. 2.6% of patients had a postoperative hematoma, 2.7% a postoperative infection, 3.9% a postoperative worsening of neurologic status; 5.4% of patients died during a 30-day period after surgery. Predictive factors of increased risk of postoperative complications were patient's age for the hematoma, a non-skull base meningioma for infection, and postoperative hematoma for the risk of neurologic worsening or 30-day mortality. Early postoperative complications in meningioma surgery have a negative impact on patient survival and postoperative neurologic status, in a disease where survival is usually not limited by the meningioma itself. In this study, we identified risk factors for early postoperative complications, the identification of at-risk populations may help to prevent the occurrence of these risk factors.
Sections du résumé
BACKGROUND
BACKGROUND
Craniotomies carry inherent risks of postoperative complications that may have a negative impact on patients' status. Recognizing and preventing surgical complications is of paramount importance, especially in meningioma surgery, where most of these tumors are benign and current management protocols are effective in terms of disease control and maintenance of higher quality of life. The objective of this study was to describe the early complications after surgery and their predictive factors in patients undergoing resection of intracranial meningiomas.
METHODS
METHODS
A partly retrospective, partly prospective review was conducted in a Norwegian population-based cohort of 1469 consecutive cases of meningioma surgery treated at the university hospitals of Oslo, totaling 11,414 patient-years of follow-up.
RESULTS
RESULTS
2.6% of patients had a postoperative hematoma, 2.7% a postoperative infection, 3.9% a postoperative worsening of neurologic status; 5.4% of patients died during a 30-day period after surgery. Predictive factors of increased risk of postoperative complications were patient's age for the hematoma, a non-skull base meningioma for infection, and postoperative hematoma for the risk of neurologic worsening or 30-day mortality.
CONCLUSIONS
CONCLUSIONS
Early postoperative complications in meningioma surgery have a negative impact on patient survival and postoperative neurologic status, in a disease where survival is usually not limited by the meningioma itself. In this study, we identified risk factors for early postoperative complications, the identification of at-risk populations may help to prevent the occurrence of these risk factors.
Identifiants
pubmed: 31082552
pii: S1878-8750(19)31284-7
doi: 10.1016/j.wneu.2019.05.010
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e851-e858Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.