Genome-wide strategies reveal target genes of Npas4l associated with vascular development in zebrafish.
Animals
Animals, Genetically Modified
Basic Helix-Loop-Helix Transcription Factors
/ metabolism
Binding Sites
/ genetics
Cell Differentiation
/ genetics
Chromosome Mapping
/ methods
Datasets as Topic
Embryo, Nonmammalian
Endothelial Cells
/ physiology
Endothelium, Vascular
/ embryology
Gene Expression Regulation, Developmental
Genomics
/ methods
LIM Domain Proteins
/ genetics
Neovascularization, Physiologic
/ genetics
T-Cell Acute Lymphocytic Leukemia Protein 1
/ genetics
Transcription Factors
/ genetics
Zebrafish
/ embryology
Zebrafish Proteins
/ genetics
ATAC-seq
Angioblast
ChIP-seq
Cloche
Endothelial cell differentiation
Npas4l
Journal
Development (Cambridge, England)
ISSN: 1477-9129
Titre abrégé: Development
Pays: England
ID NLM: 8701744
Informations de publication
Date de publication:
03 06 2019
03 06 2019
Historique:
received:
04
11
2018
accepted:
02
05
2019
pubmed:
18
5
2019
medline:
1
7
2020
entrez:
18
5
2019
Statut:
epublish
Résumé
The development of a vascular network is essential to nourish tissues and sustain organ function throughout life. Endothelial cells (ECs) are the building blocks of blood vessels, yet our understanding of EC specification remains incomplete. Zebrafish
Identifiants
pubmed: 31097478
pii: dev.173427
doi: 10.1242/dev.173427
pii:
doi:
Substances chimiques
Basic Helix-Loop-Helix Transcription Factors
0
Etv2 protein, zebrafish
0
LIM Domain Proteins
0
T-Cell Acute Lymphocytic Leukemia Protein 1
0
Transcription Factors
0
Zebrafish Proteins
0
lmo2 protein, zebrafish
0
npas4l protein, zebrafish
0
tal1 protein, zebrafish
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2019. Published by The Company of Biologists Ltd.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare no competing or financial interests.