Microbial Genes for a Circular and Sustainable Bio-PET Economy.


Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
16 05 2019
Historique:
received: 23 04 2019
revised: 10 05 2019
accepted: 13 05 2019
entrez: 19 5 2019
pubmed: 19 5 2019
medline: 19 5 2019
Statut: epublish

Résumé

Plastics have become an important environmental concern due to their durability and resistance to degradation. Out of all plastic materials, polyesters such as polyethylene terephthalate (PET) are amenable to biological degradation due to the action of microbial polyester hydrolases. The hydrolysis products obtained from PET can thereby be used for the synthesis of novel PET as well as become a potential carbon source for microorganisms. In addition, microorganisms and biomass can be used for the synthesis of the constituent monomers of PET from renewable sources. The combination of both biodegradation and biosynthesis would enable a completely circular bio-PET economy beyond the conventional recycling processes. Circular strategies like this could contribute to significantly decreasing the environmental impact of our dependence on this polymer. Here we review the efforts made towards turning PET into a viable feedstock for microbial transformations. We highlight current bottlenecks in degradation of the polymer and metabolism of the monomers, and we showcase fully biological or semisynthetic processes leading to the synthesis of PET from sustainable substrates.

Identifiants

pubmed: 31100963
pii: genes10050373
doi: 10.3390/genes10050373
pmc: PMC6562992
pii:
doi:

Substances chimiques

Biodegradable Plastics 0
Plastics 0
Polyethylene Terephthalates 0
Polymers 0
Hydrolases EC 3.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M017702/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M009769/1
Pays : United Kingdom

Déclaration de conflit d'intérêts

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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Auteurs

Manuel Salvador (M)

Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK. m.salvadordelara@surrey.ac.uk.

Umar Abdulmutalib (U)

Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK. u.abdulmutalib@surrey.ac.uk.

Jaime Gonzalez (J)

Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK. j.gonzalezgutierrezdelaconch@surrey.ac.uk.

Juhyun Kim (J)

Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK. juhyun.kim@surrey.ac.uk.

Alex A Smith (AA)

Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK. alex.smith@surrey.ac.uk.

Jean-Loup Faulon (JL)

Micalis Institute, INRA, AgroParisTech, Université Paris-Saclay, 78350 Jouy-en-Josas, France. jean-loup.faulon@inra.fr.
SYNBIOCHEM Centre, Manchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, UK. jean-loup.faulon@inra.fr.
CNRS-UMR8030/Laboratoire iSSB, Université Paris-Saclay, 91000 Évry, France. jean-loup.faulon@inra.fr.

Ren Wei (R)

Department of Microbiology and Bioprocess Technology, Institute of Biochemistry, Leipzig University, 04103 Leipzig, Germany. wei@uni-leipzig.de.

Wolfgang Zimmermann (W)

Department of Microbiology and Bioprocess Technology, Institute of Biochemistry, Leipzig University, 04103 Leipzig, Germany. wolfgang.zimmermann@uni-leipzig.de.

Jose I Jimenez (JI)

Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK. j.jimenez@surrey.ac.uk.

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Classifications MeSH