Influence of Mammography Volume on Radiologists' Performance: Results from BreastScreen Norway.

Background Several European screening mammography programs that use independent double reading with consensus recommend an annual minimum reading volume of 5000 mammograms per radiologist. This recommendation is based only on expert opinion, and the influence of reading volume on performance in such programs is unknown. Purpose To examine the influence of annual and cumulative reading volume on radiologists' reading performance for digital mammography in a screening program that uses independent double reading with consensus. Materials and Methods This retrospective study included data from digital mammographic examinations in BreastScreen Norway obtained from 2006 to 2016. Multilevel mixed-effects models were used to determine how sensitivity, rate of screening-detected breast cancer (SDC), and false-positive rate (FPR) before and after consensus meeting related to annual and cumulative reading volume. Results The study included 2 373 433 readings performed by 121 radiologists. The median annual reading volume ranged from 153 to 19 500 mammograms, and the median cumulative reading volume was 30 566 mammograms. Sensitivity and SDC rate were relatively stable at 87% to 90% and 4.9 to 4.7 per 1000 readings (0.49% and 0.47%), respectively, between 100 and 10 000 annual readings and at 88% to 89% and 4.8 to 4.9 per 1000 readings (0.48% and 0.49%) between 500 and 100 000 cumulative readings. There was a decreasing trend with higher annual volumes (