Sox9 regulates the luminal stem/progenitor cell properties of salivary glands.


Journal

Experimental cell research
ISSN: 1090-2422
Titre abrégé: Exp Cell Res
Pays: United States
ID NLM: 0373226

Informations de publication

Date de publication:
01 09 2019
Historique:
received: 28 01 2019
revised: 20 05 2019
accepted: 28 05 2019
pubmed: 4 6 2019
medline: 23 6 2020
entrez: 3 6 2019
Statut: ppublish

Résumé

Exocrine glands share a common morphology consisting of ductal, acinar, and basal/myoepithelial cells, but their functions and mechanisms of homeostasis differ among tissues. Salivary glands are an example of exocrine glands, and they have been reported to contain multipotent stem cells that differentiate into other tissues. In this study, we purified the salivary gland stem/progenitor cells of adult mouse salivary glands using the cell surface marker CD133 by flow cytometry. CD133

Identifiants

pubmed: 31153924
pii: S0014-4827(19)30281-2
doi: 10.1016/j.yexcr.2019.05.030
pii:
doi:

Substances chimiques

AC133 Antigen 0
PROM1 protein, human 0
Prom1 protein, mouse 0
SOX9 Transcription Factor 0
SOX9 protein, human 0
Sox9 protein, mouse 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

111449

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Junichi Tanaka (J)

Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo, 142-8555, Japan.

Yo Mabuchi (Y)

Department of Biochemistry and Biophysics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan.

Kenji Hata (K)

Department of Molecular and Cellular Biochemistry, Osaka University Graduate School of Dentistry, Osaka, 565-0871, Japan.

Rika Yasuhara (R)

Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo, 142-8555, Japan.

Koki Takamatsu (K)

Department of Oral and Maxillofacial Surgery, School of Dentistry, Showa University, Tokyo, 142-8555, Japan.

Satoko Kujiraoka (S)

Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo, 142-8555, Japan.

Akane Yukimori (A)

Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo, 142-8555, Japan.

Ikuko Takakura (I)

Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo, 142-8555, Japan; Department of Dentistry, Jikei University School of Medicine, Tokyo, 201-8601, Japan.

Hidetoshi Sumimoto (H)

Department of Medical Oncology and Cancer Center, Shiga University of Medical Science, Shiga, 520-2192, Japan.

Toshiyuki Fukada (T)

Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo, 142-8555, Japan; Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, 770-8514, Japan.

Masayuki Azuma (M)

Department of Oral Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, 770-8503, Japan.

Haruhiko Akiyama (H)

Department of Orthopaedic Surgery, School of Medicine, Gifu University, Gifu, 501-1112, Japan.

Riko Nishimura (R)

Department of Molecular and Cellular Biochemistry, Osaka University Graduate School of Dentistry, Osaka, 565-0871, Japan.

Toshikazu Shimane (T)

Head and Neck Oncology Center, Showa University, Tokyo, 142-8555, Japan.

Kenji Mishima (K)

Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Tokyo, 142-8555, Japan. Electronic address: mishima-k@dent.showa-u.ac.jp.

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Classifications MeSH