Prevalence and incidence of inflammatory bowel disease in two Italian islands, Sicily and Sardinia: A report based on health information systems.


Journal

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
ISSN: 1878-3562
Titre abrégé: Dig Liver Dis
Pays: Netherlands
ID NLM: 100958385

Informations de publication

Date de publication:
09 2019
Historique:
received: 04 02 2019
revised: 05 05 2019
accepted: 07 05 2019
pubmed: 10 6 2019
medline: 9 4 2020
entrez: 10 6 2019
Statut: ppublish

Résumé

Few epidemiological data about inflammatory bowel disease (IBD) in Italy are available. To estimate IBD prevalence and incidence in two Italian regions - Sicily and Sardinia - using regional health information systems. Data from hospital discharges and disease-specific payment exemptions register were retrieved and underwent record-linkage procedures. Standardized prevalence and incidence were calculated as rates per 100,000 inhabitants. In Sicily, during the year 2013, the overall IBD incidence rate was 27 per 100,000 inhabitants, while the incidence rate of Crohn's disease (CD) was 16 for males and 13 for females, and the incidence of ulcerative colitis (UC) was 15 and 11 for males and females, respectively. At the date of December 31st, 2013, the standardized prevalence rate of IBD was estimated at 300 cases per 100,000 inhabitants. In Sardinia, during the period 2008-2010, the average IBD incidence rate per 100,000 was 15, with an incidence rate of 5 per 100,000 for CD, and 10 per 100,000 for UC, while the standardized prevalence rate of IBD was estimated at 187 cases per 100,000 inhabitants. The particularly high incidence of CD in Sicily, and the marked difference of IBD occurrence between the two islands deserve future investigations.

Sections du résumé

BACKGROUND
Few epidemiological data about inflammatory bowel disease (IBD) in Italy are available.
AIMS
To estimate IBD prevalence and incidence in two Italian regions - Sicily and Sardinia - using regional health information systems.
METHODS
Data from hospital discharges and disease-specific payment exemptions register were retrieved and underwent record-linkage procedures. Standardized prevalence and incidence were calculated as rates per 100,000 inhabitants.
RESULTS
In Sicily, during the year 2013, the overall IBD incidence rate was 27 per 100,000 inhabitants, while the incidence rate of Crohn's disease (CD) was 16 for males and 13 for females, and the incidence of ulcerative colitis (UC) was 15 and 11 for males and females, respectively. At the date of December 31st, 2013, the standardized prevalence rate of IBD was estimated at 300 cases per 100,000 inhabitants. In Sardinia, during the period 2008-2010, the average IBD incidence rate per 100,000 was 15, with an incidence rate of 5 per 100,000 for CD, and 10 per 100,000 for UC, while the standardized prevalence rate of IBD was estimated at 187 cases per 100,000 inhabitants.
CONCLUSIONS
The particularly high incidence of CD in Sicily, and the marked difference of IBD occurrence between the two islands deserve future investigations.

Identifiants

pubmed: 31176630
pii: S1590-8658(19)30596-1
doi: 10.1016/j.dld.2019.05.017
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1270-1274

Informations de copyright

Copyright © 2019 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Auteurs

Fabio Salvatore Macaluso (FS)

IBD Unit, "Villa Sofia-Cervello" Hospital, Palermo, Italy. Electronic address: fsmacaluso@gmail.com.

Giammarco Mocci (G)

Gastroenterology Unit, "G. Brotzu" Hospital, Cagliari, Italy.

Ambrogio Orlando (A)

IBD Unit, "Villa Sofia-Cervello" Hospital, Palermo, Italy.

Salvatore Scondotto (S)

Department of Health Activities and Epidemiological Observatory, Health Department of Sicilian Region, Palermo, Italy.

Giovanna Fantaci (G)

Department of Health Activities and Epidemiological Observatory, Health Department of Sicilian Region, Palermo, Italy.

Antonello Antonelli (A)

Department of Hygiene, Health and Social Assistance, Sardinia Region, Cagliari, Italy.

Salvatore Leone (S)

AMICI Onlus, Italy.

Enrica Previtali (E)

AMICI Onlus, Italy.

Francesco Cabras (F)

Gastroenterology Unit, "G. Brotzu" Hospital, Cagliari, Italy.

Mario Cottone (M)

IBD Unit, "Villa Sofia-Cervello" Hospital, Palermo, Italy.

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