Chemical synthesis and characterization of a new quinazolinedione competitive antagonist for strigolactone receptors with an unexpected binding mode.

Arabidopsis / chemistry Arabidopsis Proteins / antagonists & inhibitors Crystallography, X-Ray Petunia / chemistry Protein Binding Quinazolinones / chemical synthesis Receptors, Cell Surface / antagonists & inhibitors
crystallography hydrolases inhibition plant hormones small molecules strigolactone

Journal

The Biochemical journal
ISSN: 1470-8728
Titre abrégé: Biochem J
Pays: England
ID NLM: 2984726R

Informations de publication

Date de publication:
28 06 2019
Historique:
received: 16 04 2019
revised: 06 06 2019
accepted: 11 06 2019
pubmed: 13 6 2019
medline: 12 2 2020
entrez: 13 6 2019
Statut: epublish

Résumé

Strigolactones (SLs) are multifunctional plant hormones regulating essential physiological processes affecting growth and development. In vascular plants, SLs are recognized by α/β hydrolase-fold proteins from the D14/DAD2 (Dwarf14/Decreased Apical Dominance 2) family in the initial step of the signaling pathway. We have previously discovered that

Identifiants

DOI: 10.1042/BCJ20190288 PMID: 31186286
pubmed: 31186286
pii: BCJ20190288
doi: 10.1042/BCJ20190288
doi:

Substances chimiques

Arabidopsis Proteins 0
Quinazolinones 0
Receptors, Cell Surface 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1843-1856

Informations de copyright

© 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

Auteurs

Cyril Hamiaux (C)

The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand cyril.hamiaux@plantandfood.co.nz.
ORCID: 0000-0001-9198-3441

Lesley Larsen (L)

Department of Chemistry, University of Otago, Dunedin, New Zealand.

Hui Wen Lee (HW)

The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand.
School of Biological Sciences, University of Auckland, Auckland, New Zealand.

Zhiwei Luo (Z)

The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand.

Prachi Sharma (P)

The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand.
School of Biological Sciences, University of Auckland, Auckland, New Zealand.

Bill C Hawkins (BC)

Department of Chemistry, University of Otago, Dunedin, New Zealand.

Nigel B Perry (NB)

Department of Chemistry, University of Otago, Dunedin, New Zealand.
Department of Chemistry, The New Zealand Institute for Plant and Food Research Limited, University of Otago, Dunedin, New Zealand.

Kimberley C Snowden (KC)

The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Brassicaceae › Arabidopsis › Chemical synthesis and characterization of a...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines végétales › Protéines d'Arabidopsis › Chemical synthesis and characterization of a...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Chemical synthesis and characterization of a...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Solanales › Solanaceae › Petunia › Chemical synthesis and characterization of a...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Chemical synthesis and characterization of a...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinazolines › Quinazolinones › Chemical synthesis and characterization of a...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Chemical synthesis and characterization of a...