Renal Artery Coverage During Endovascular Aneurysm Repair for Ruptured Abdominal Aortic Aneurysm.


Journal

Annals of vascular surgery
ISSN: 1615-5947
Titre abrégé: Ann Vasc Surg
Pays: Netherlands
ID NLM: 8703941

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 03 02 2019
revised: 01 05 2019
accepted: 25 05 2019
pubmed: 16 6 2019
medline: 17 3 2020
entrez: 16 6 2019
Statut: ppublish

Résumé

Coverage of one or both renal arteries may be required to facilitate endovascular aneurysm repair (EVAR) in patients who are not candidates for open surgery in ruptured abdominal aortic aneurysms (rAAAs). We sought to understand the consequences of renal coverage during these emergent procedures. Using the VQI data set from 2013 to 2018, we selected patients who had undergone EVAR for rAAA. Patients were distinguished by whether they had none, unilateral, or bilateral renal artery coverage. Patients were excluded if they were previously on dialysis or had an intervention to preserve renal perfusion. Primary endpoints included inhospital mortality, composite permanent dialysis/30-day death, and 1-year survival. Overall, there were 2,278 patients presenting with ruptured aneurysms. Most patients had no renal artery coverage (n = 2,230; 98%), followed by single renal artery coverage (n = 30; 1.2%), and finally bilateral renal artery coverage (n = 18, 0.8%). On multivariate regression, bilateral renal coverage was associated with increased odds of inhospital mortality (odds ratio [OR] = 5.7, ±4; P = 0.030), permanent dialysis/30-day death (OR = 9.5, ±7; P = 0.016), and permanent dialysis (OR = 47.5, ±47; P < 0.001). Two patients with bilateral renal coverage did not suffer permanent dialysis/death. Single renal artery coverage significantly increased the odds of permanent dialysis/30-day death (OR = 2.8, ±1.6; P = 0.044) driven mainly by its effect on the outcome of permanent dialysis (OR = 12.3, ±6; P < 0.001). Unadjusted Kaplan-Meier one-year survival estimates were significantly lower with bilateral renal coverage (hazard ratio [HR] = 3.4, P = 0.0002). Bilateral coverage remained a significant predictor on adjusted analysis (HR = 3.5, P = 0.002); however, single renal coverage did not significantly affect survival in unadjusted or adjusted models. Bilateral renal coverage in rAAA significantly increases inhospital mortality and lowers long-term survival. While single renal artery coverage increases the risk of permanent dialysis/30-day death driven mainly by its effect on permanent dialysis, it does not significantly affect inhospital mortality or one-year survival and may be a viable option for select patients with rAAAs.

Identifiants

pubmed: 31201979
pii: S0890-5096(19)30404-2
doi: 10.1016/j.avsg.2019.05.005
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

63-69

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Adam Tanious (A)

Division of Vascular Surgery, Massachusetts General Hospital, Boston, MA. Electronic address: atanious@mgh.harvard.edu.

Laura T Boitano (LT)

Division of Vascular Surgery, Massachusetts General Hospital, Boston, MA.

Linda J Wang (LJ)

Division of Vascular Surgery, Massachusetts General Hospital, Boston, MA.

Murray L Shames (ML)

Division of Vascular Surgery, University of South Florida, Tampa, FL.

Jason T Lee (JT)

Division of Vascular Surgery, Stanford University, Stanford, CA.

Matthew J Eagleton (MJ)

Division of Vascular Surgery, Massachusetts General Hospital, Boston, MA.

W Darrin Clouse (WD)

Division of Vascular and Endovascular Surgery, University of Virginia, Charlottesville, VA.

Mark F Conrad (MF)

Division of Vascular Surgery, Massachusetts General Hospital, Boston, MA.

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