[Investigations into the distribution of neohistamine methylsulfate in the organism of the warm blooded animals following its intragastric administration].

Izuchenie raspredeleniia neostigmina metilsul'fata v organizme teplokrovnykh zhivotnykh posle vnutrizheludochnogo vvedeniia.

Journal

Sudebno-meditsinskaia ekspertiza
ISSN: 0039-4521
Titre abrégé: Sud Med Ekspert
Pays: Russia (Federation)
ID NLM: 0404546

Informations de publication

Date de publication:
2019
Historique:
entrez: 20 6 2019
pubmed: 20 6 2019
medline: 2 8 2019
Statut: ppublish

Résumé

The objective - of the present study was to elucidate the specific features of the distribution of neohistamine methylsulfate (proserin) in the organism of the omnivorous warm blooded animals following its intragastric administration. The analytical methods included TLC, HPLC, and UV-spectrophotometry. Neohistamine methylsulfate was administered intrgastrically to the male Wistar rats at a dose equivalent to the triple LD Цель исследования - выявить особенности распределения неостигмина метилсульфата (прозерина) в организме всеядных теплокровных животных после внутрижелудочного введения данного вещества. Как методы анализа рассмотрены ТСХ, ВЭЖХ и УФ-спектрофотометрия. Крысам-самцам породы Wistar вводили в желудок тройную LD

Autres résumés

Type: Publisher (rus)
Цель исследования - выявить особенности распределения неостигмина метилсульфата (прозерина) в организме всеядных теплокровных животных после внутрижелудочного введения данного вещества. Как методы анализа рассмотрены ТСХ, ВЭЖХ и УФ-спектрофотометрия. Крысам-самцам породы Wistar вводили в желудок тройную LD

Identifiants

pubmed: 31213591
doi: 10.17116/sudmed20196202140
doi:

Substances chimiques

Histamine 820484N8I3

Types de publication

Journal Article

Langues

rus

Pagination

40-47

Auteurs

M I Alekhina (MI)

Department of Pharmaceutical Chemistry and pharmaceutical Technologies, N.N. Burdenko Voronezh State Medical University, Ministry of Health of the Russia, Voronezh, Russia, 394036.

V K Shormanov (VK)

Department of Pharmaceutical, Toxicological and Analytical Chemistry, Kursk State Medical University, Kursk, Russia, 305041.

T N Nikitina (TN)

Department of Pharmaceutical Chemistry and pharmaceutical Technologies, N.N. Burdenko Voronezh State Medical University, Ministry of Health of the Russia, Voronezh, Russia, 394036.

A M Markelova (AM)

Department of Pharmaceutical, Toxicological and Analytical Chemistry, Kursk State Medical University, Kursk, Russia, 305041.

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Classifications MeSH