Topical application of coconut oil to the skin of preterm infants: a systematic review.
Administration, Cutaneous
Anti-Infective Agents
/ therapeutic use
Coconut Oil
/ therapeutic use
Dehydration
/ prevention & control
Emollients
/ therapeutic use
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases
/ prevention & control
Neonatal Sepsis
/ prevention & control
Randomized Controlled Trials as Topic
Skin Care
/ methods
Treatment Outcome
Weight Gain
Coconut oil
Preterm infant
Sepsis
Skin
Topical
Trans-epidermal water loss
Journal
European journal of pediatrics
ISSN: 1432-1076
Titre abrégé: Eur J Pediatr
Pays: Germany
ID NLM: 7603873
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
28
03
2019
accepted:
05
06
2019
revised:
04
06
2019
pubmed:
4
7
2019
medline:
21
1
2020
entrez:
4
7
2019
Statut:
ppublish
Résumé
Preterm infants are at risk of increased trans-epidermal water loss and infections due to epidermal immaturity. The emollient and anti-infective properties of coconut oil make it a potentially beneficial topical agent for this population. We aimed to systematically review randomised trials assessing the effects of topical coconut oil in preterm infants. Medline, EMBASE, Cochrane Central Register of Controlled Trials and CINAHL were searched. Seven trials (n = 727 infants) were included. The majority of trials included relatively mature infants (gestation > 32 weeks, birth weight > 1200 g). The duration of intervention (5-31 days) and outcomes of interest varied among included studies. Meta-analysis using random effects model found significantly lower incidence of hospital-acquired blood stream infections (HABSI) in the coconut oil group (11/164 vs 32/166; relative risk 0.35, 95% confidence interval 0.18, 0.67, p = 0.001; I
Identifiants
pubmed: 31267223
doi: 10.1007/s00431-019-03407-7
pii: 10.1007/s00431-019-03407-7
doi:
Substances chimiques
Anti-Infective Agents
0
Emollients
0
Coconut Oil
Q9L0O73W7L
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1317-1324Références
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