A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat urine.


Journal

Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488

Informations de publication

Date de publication:
27 Sep 2019
Historique:
received: 29 04 2019
revised: 24 06 2019
accepted: 26 06 2019
pubmed: 10 7 2019
medline: 11 10 2019
entrez: 10 7 2019
Statut: ppublish

Résumé

A comprehensive Collision Cross Section (CCS) library was obtained via Travelling Wave Ion Guide mobility measurements through direct infusion (DI). The library consists of CCS and Mass Spectral (MS) data in negative and positive ElectroSpray Ionisation (ESI) mode for 463 and 479 endogenous metabolites, respectively. For both ionisation modes combined,

Identifiants

pubmed: 31285057
pii: S0021-9673(19)30665-X
doi: 10.1016/j.chroma.2019.06.056
pii:
doi:

Substances chimiques

Amines 0

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

386-396

Subventions

Organisme : Medical Research Council
ID : MR/N006321/1
Pays : United Kingdom

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Leanne C Nye (LC)

Waters Corporation, Wilmslow, SK9 4AX, UK; Section of Computational and Systems Medicine, Imperial College, London, SW7 2AZ, UK.

Jonathan P Williams (JP)

Waters Corporation, Wilmslow, SK9 4AX, UK.

Nyasha C Munjoma (NC)

Waters Corporation, Wilmslow, SK9 4AX, UK; Section of Computational and Systems Medicine, Imperial College, London, SW7 2AZ, UK.

Marine P M Letertre (MPM)

Section of Computational and Systems Medicine, Imperial College, London, SW7 2AZ, UK.

Muireann Coen (M)

Section of Computational and Systems Medicine, Imperial College, London, SW7 2AZ, UK; Safety and ADME Translational Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Unit 310, Cambridge Science Park, Milton Road, Cambridge, CB4 0WG, UK.

Robbin Bouwmeester (R)

VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium; Faculty of Medicine and Health Sciences, Department of Biochemistry, Ghent University, Ghent, Belgium.

Lennart Martens (L)

VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium; Faculty of Medicine and Health Sciences, Department of Biochemistry, Ghent University, Ghent, Belgium.

Jonathan R Swann (JR)

Section of Computational and Systems Medicine, Imperial College, London, SW7 2AZ, UK.

Jeremy K Nicholson (JK)

Australian National Phenome Centre, Murdoch University, Harry Perkins Building, Perth, WA, Australia.

Robert S Plumb (RS)

Waters Corporation, Milford, MA, USA.

Michael McCullagh (M)

Waters Corporation, Wilmslow, SK9 4AX, UK.

Lee A Gethings (LA)

Waters Corporation, Wilmslow, SK9 4AX, UK.

Steven Lai (S)

Waters Corporation, Beverly, MA, USA.

James I Langridge (JI)

Waters Corporation, Wilmslow, SK9 4AX, UK.

Johannes P C Vissers (JPC)

Waters Corporation, Wilmslow, SK9 4AX, UK. Electronic address: hans_vissers@waters.com.

Ian D Wilson (ID)

Section of Computational and Systems Medicine, Imperial College, London, SW7 2AZ, UK. Electronic address: i.wilson@imperial.ac.uk.

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Classifications MeSH