Rational development of transformation in Clostridium thermocellum ATCC 27405 via complete methylome analysis and evasion of native restriction-modification systems.

Clostridium thermocellum Methylome Real-time sequencing Restriction–modification systems Single molecule Whole-genome bisulfite sequencing

Journal

Journal of industrial microbiology & biotechnology
ISSN: 1476-5535
Titre abrégé: J Ind Microbiol Biotechnol
Pays: Germany
ID NLM: 9705544

Informations de publication

Date de publication:
Oct 2019
Historique:
received: 02 03 2019
accepted: 11 07 2019
pubmed: 26 7 2019
medline: 23 1 2020
entrez: 26 7 2019
Statut: ppublish

Résumé

A major barrier to both metabolic engineering and fundamental biological studies is the lack of genetic tools in most microorganisms. One example is Clostridium thermocellum ATCC 27405

Identifiants

pubmed: 31342224
doi: 10.1007/s10295-019-02218-x
pii: 10.1007/s10295-019-02218-x
pmc: PMC6791906
doi:

Substances chimiques

DNA Restriction-Modification Enzymes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1435-1443

Subventions

Organisme : Biological and Environmental Research
ID : Center for Bioenergy Innovation
Organisme : Biological and Environmental Research
ID : BioEnergy Science Center

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Auteurs

Lauren A Riley (LA)

Bredesen Center, University of Tennessee, Knoxville, TN, 37996, USA.
Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, USA.

Lexiang Ji (L)

Institute of Bioinformatics, University of Georgia, Athens, GA, 30602, USA.

Robert J Schmitz (RJ)

Department of Genetics, University of Georgia, Athens, GA, 30602, USA.

Janet Westpheling (J)

Department of Genetics, University of Georgia, Athens, GA, 30602, USA.

Adam M Guss (AM)

Bredesen Center, University of Tennessee, Knoxville, TN, 37996, USA. gussam@ornl.gov.
Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, USA. gussam@ornl.gov.

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Classifications MeSH