Synthetic Multienzyme Complexes, Catalytic Nanomachineries for Cascade Biosynthesis


Journal

ACS nano
ISSN: 1936-086X
Titre abrégé: ACS Nano
Pays: United States
ID NLM: 101313589

Informations de publication

Date de publication:
24 09 2019
Historique:
pubmed: 30 7 2019
medline: 28 8 2020
entrez: 30 7 2019
Statut: ppublish

Résumé

Multienzyme complexes, or metabolons, are assemblies or clusters of sequential enzymes that naturally exist in metabolic pathways. These nanomachineries catalyze the conversion of metabolites more effectively than the freely floating enzymes by minimizing the diffusion of intermediates

Identifiants

pubmed: 31356751
doi: 10.1021/acsnano.9b03631
doi:

Substances chimiques

Multienzyme Complexes 0
Proteins 0
Carotenoids 36-88-4

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9895-9906

Auteurs

Rui Wang (R)

Department of Biomedical Sciences , City University of Hong Kong , Kowloon , Hong Kong SAR, China.

Tian Ma (T)

Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences , Wuhan University , Wuhan 430071 , China.

Liang Zhang (L)

Department of Biomedical Sciences , City University of Hong Kong , Kowloon , Hong Kong SAR, China.

Tiangang Liu (T)

Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences , Wuhan University , Wuhan 430071 , China.

Fei Sun (F)

Center for Biological Imaging, Core Facilities for Protein Science, Institute of Biophysics, CAS, Beijing, China; University of Chinese Academy of Sciences, Beijing, China;National Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics , Chinese Academy of Sciences , Beijing 100101 , China.

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Classifications MeSH